Vomino 5 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 28.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Monicopharma ltd |
| Also available as |
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Epigastric sense of fullness
- Abdominal distension
- Upper abdominal pain
- Eructation
- Flatulence
- Early satiety
- Nausea and vomiting
- Heartburn
- Non-ulcer dyspepsia
- Acute nausea and vomiting
- Parkinson's disease
- Radiotherapy-induced nausea and vomiting
- Drug therapy-induced nausea and vomiting
- Barium transit in radiological studies
Pharmacology
- Dopamine antagonist
- Chemoreceptor Trigger Zone (CTZ) blocking
- Gastroprokinetic action
- Motility regulation
- Gastric emptying facilitation
- Enhanced peristalsis
- Regulation of pylorus contraction
Dosage & Administration
- Oral administration
- 15-30 minutes before meals
- Usual recommended oral dose for adults: 10-20 mg every 6-8 hours
- Maximum dose for adults: 80 mg daily
- Rectal administration for adults: 30-60 mg every 4-8 hours
- Dosage for children based on body weight
Interaction
- Anticholinergic drug antagonism
- Lowered oral bioavailability with antacids and antisecretory drugs
- Metabolic pathway through CYP3A4
- Inhibition of CYP3A4 by certain drugs
- Influence on drug absorption
- Action potentiation with neuroleptics
- Suppression of unwanted peripheral effects of dopaminergic agonists
Contraindications
- Known hypersensitivity to domperidone
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction
- Perforation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Neuroendocrinological phenomena
- Allergic reactions such as rash and urticaria
- Gastrointestinal side effects
Pregnancy & Lactation
- Caution during first trimester of pregnancy
- Excretion in breast milk
- Breastfeeding not recommended
- Effects on ability to drive
Precautions & Warnings
- Absolute caution in children
- Increased risk of extra-pyramidal reactions in young children
- Caution in patients with hepatic impairment
Use in Special Populations
- Caution in infants
- Use in liver disorders
- Use in kidney disorders
- Adjustment of dosing frequency in renal insufficiency
Overdose Effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
- Activated charcoal administration
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
- Gastrointestinal motility regulation
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure Image: [Link to chemical structure image]
Common Questions about Vomino 5 mg/5 ml Suspension
- Usage for treating nausea and vomiting
- Relief of nausea, vomiting, and indigestion
- Dizziness and sleepiness as potential side effects
- Avoidance of alcohol consumption
- Management of dry mouth as a side effect
- Reporting of persistent adverse symptoms
- Consultation for prolonged use