Vomitop 10 mg (Tablet)
Unit Price: ৳ 3.20 (10 x 10: ৳ 320.00)
Strip Price: ৳ 32.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Title
- Vomitop 10 mg Tablet
Categories
- Medicine
- Pharmaceutical
Description
- A dopamine antagonist medication for treating nausea and vomiting.
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
DosageAdministration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults: 10-20 mg every 6-8 hours daily
- Maximum dose of 80 mg daily for adults
- Rectal administration: 30-60 mg every 4-8 hours for adults
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in Chemoreceptor Trigger Zone (CTZ) and stomach
- Restores normal motility and tone of the upper gastrointestinal tract
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Increases esophageal peristalsis
Interaction
- Contraindicated with anticholinergic drugs
- Main metabolic pathway through CYP3A4
- Inhibition of CYP3A4 by certain drugs may increase plasma levels
- Does not potentiate neuroleptics
- Suppresses unwanted peripheral effects of dopaminergic agonists
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor
SideEffects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Increased plasma prolactin level
- Rare allergic reactions
PregnancyLactation
- Use with caution during first trimester
- Excreted in breast milk
- Not recommended for nursing mothers
PrecautionsWarnings
- Use with caution in children due to risk of extra-pyramidal reactions
- Use with caution in patients with hepatic impairment
SpecialPopulations
- Use in infants with caution and close medical supervision
- Use with caution in patients with hepatic impairment
- Review regularly in patients on prolonged therapy
OverdoseEffects
- Drowsiness
- Disorientation
- Extrapyramidal reactions, especially in children
TherapeuticClass
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
StorageConditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
ChemicalStructure
- MolecularFormula: C22H24ClN5O2
- ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg
CommonQuestions
- Usage: Relieves nausea, vomiting and indigestion
- Administration: Take before meals as per doctor's prescription
- Precautions:
- May cause dizziness and sleepiness
- Avoid alcohol consumption
- Inform doctor about any unusual symptoms
- Do not take for longer than 7 days without consulting doctor