Xeridon 10 mg (Tablet)

Title

• Xeridon 10 mg Tablet

Categories

• Medicine
• Pharmaceuticals

Description

• Dopamine antagonist medication for treating nausea and vomiting
• Gastroprokinetic action based on blocking effect of dopamine receptors
• Restores normal motility and tone of the upper gastrointestinal tract
• Facilitates gastric emptying and enhances antral and duodenal peristalsis
• Regulates contraction of the pylorus
• Increases esophageal peristalsis and lower esophageal sphincter pressure
• Speeds barium transit in follow-through radiological studies
• Should be used with absolute caution in children
• Renal insufficiency impacts elimination half-life and plasma drug levels

Color Options

• White

Dosage & Administration

• To be taken 15-30 minutes before meals
• Usual recommended oral dose for adults: 10-20 mg every 6-8 hours daily
• Maximum dose for adults: 80 mg daily
• Recommended dose for children: 0.2-0.4 mg/kg body weight every 6-8 hours daily
• By rectum in suppositories: 30-60 mg every 4-8 hours for adults

Indications

• Dyspeptic symptom complex
• Acute nausea and vomiting
• Parkinson's disease
• Radiological studies

Interaction

• Antagonized by concomitant administration of anticholinergic drugs
• Should not be given simultaneously with antacids and antisecretory drugs
• Main metabolic pathway through CYP3A4
• Could influence absorption of concomitantly orally administered drugs
• Does not potentiate the action of neuroleptics or dopaminergic agonists

Contraindications

• Hypersensitivity to the drug
• Neonates
• Gastrointestinal hemorrhage
• Mechanical obstruction or perforation
• Prolactin releasing pituitary tumor

Side Effects

• Transient intestinal cramps
• Rare extrapyramidal phenomena
• Increase in plasma prolactin level
• Hyperprolactinaemia may give rise to neuroendocrinological phenomena
• Rare allergic reactions such as rash and urticaria

Pregnancy & Lactation

• Should only be used during the first trimester if justified by the therapeutic benefit
• No evidence of increase in the risk of malformations in humans
• Excreted in breast milk of lactating rats
• Not recommended for nursing mothers unless expected benefits outweigh potential risk

Precautions & Warnings

• Increased risk of extra-pyramidal reactions in young children
• Highly metabolized in the liver, caution required in hepatic impairment

Use in Special Populations

• Great caution required for infants under 1 year of age due to incomplete blood-brain barrier development
• Use with caution in patients with hepatic or renal impairment

Overdose Effects

• Drowsiness
• Disorientation
• Extrapyramidal reactions
• Activated charcoal administration recommended

Therapeutic Class

• Motility Stimulants
• Dopamine antagonist
• Prokinetic drugs

Storage Conditions

• Store below 30°C
• Protected from light and moisture
• Keep out of children's reach

Chemical Structure

• Molecular Formula: C22H24ClN5O2

Commonly Asked Questions

• Used for treating nausea and vomiting
• Helps relieve nausea, vomiting and indigestion
• May cause dizziness and sleepiness
• Avoid consuming alcohol when taking the tablet
• Dry mouth may occur as a side effect
• Inform doctor if experiencing specific symptoms
• Avoid prolonged use without doctor's consultation

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