Xeridon 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 40.00

Medicine Details

Category Details
Generic Domperidone maleate
Company Jenphar bangladesh ltd
Also available as
Xeridon 10 mg tablet

Title

Xeridon 5 mg/5 ml Suspension

Categories

  • Medicine
  • Health
  • Pharmaceutical

Description

Dopamine antagonist medication for dyspeptic symptom complex, acute nausea and vomiting, Parkinson's disease, and radiological studies.

DosageAndAdministration

  • Should be taken 15-30 minutes before meals
  • Usual recommended oral dose for adults: 10-20 mg every 6-8 hours daily
  • Maximum dose for adults: 80 mg daily
  • Dosage varies for children based on body weight
  • Rectal administration for specific cases

Pharmacology

Restores normal motility and tone of the upper gastrointestinal tract, facilitates gastric emptying, enhances antral and duodenal peristalsis, regulates contraction of the pylorus, increases esophageal peristalsis, and lower esophageal sphincter pressure

Indications

  • Delayed gastric emptying
  • Gastroesophageal reflux
  • Esophagitis
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Interactions

  • Anticholinergic drugs may antagonize its effect
  • Antacids and antisecretory drugs should not be given simultaneously
  • Metabolic pathway through CYP3A4
  • Potential influence on the absorption of concomitantly orally administered drugs

Contraindications

  • Known hypersensitivity to the drug
  • Neonates
  • Gastrointestinal hemorrhage
  • Mechanical obstruction or perforation
  • Prolactin releasing pituitary tumor (prolactinoma)

SideEffects

  • Rare gastrointestinal cramps
  • Rare extrapyramidal phenomena
  • Possible increase in plasma prolactin level
  • Rare allergic reactions such as rash and urticaria

PregnancyAndLactation

  • Usage during first trimester may be justified by anticipated therapeutic benefit
  • Excreted in breast milk
  • Not recommended during nursing unless benefits outweigh risks
  • Does not affect mental alertness

PrecautionsAndWarnings

  • Increased risk of extra-pyramidal reactions in young children
  • Caution in patients with hepatic impairment

UseInSpecialPopulations

  • Great caution in giving to infants
  • Caution in patients with hepatic impairment
  • Dosing frequency adjustment in severe renal insufficiency

OverdoseEffects

  • Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
  • Treatment with activated charcoal and close patient observation recommended

TherapeuticClass

  • Motility Stimulants
  • Motility stimulants/Dopamine antagonist
  • Prokinetic drugs

StorageConditions

Store below 30°C, protected from light and moisture, keep out of children's reach

ChemicalStructure

  • MolecularFormula: C22H24ClN5O2
  • ChemicalStructureURL: https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg

CommonQuestions

  • Usage: Relief of nausea, vomiting, and indigestion
  • Tips:
    • Take before meals as per prescribed dose and duration
    • Avoid alcohol consumption while using
    • Watch out for side effects such as dizziness and dry mouth

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