Racetril 30 mg/sachet (Oral Powder)
30 mg sachet: ৳ 10.00 (30's pack: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Racecadotril |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Symptomatic treatment of acute diarrhea
Description
- Pure intestinal antisecretory active substance
- Decreases intestinal hypersecretion of water and electrolytes
- Rapidly absorbed and hydrolysed to thiorphan
- Protects enkephalins from enzymatic degradation
- Exerts rapid antidiarrhoeal action
Pharmacology
- Increases availability of endogenous opioids (enkephalins)
- Inhibits membrane-bound enkephalinase
- Mediates effect through δ receptor activation
- Induces a selective increase in Cl absorption
Dosage & Administration
- Adult dosage: one capsule initially, then one capsule three times daily
- Children dosage based on body weight
- Infants less than 9 kg: one 10 mg sachet 3 times daily
- Infants from 9 kg to 13 kg: two 10 mg sachets 3 times daily
- Children from 13 kg to 27 kg: one 30mg sachet 3 times daily
- Children of more than 27 kg: two 30mg sachets 3 times daily
Interaction
- No drug interactions found with Loperamide or Nifuroxazide
Contraindications
- Hypersensitivity to Racecadotril or to any of the excipients
Side Effects
- Headache
- Erythema multiforme
- Urticaria
- Angioedema
Pregnancy & Lactation
- Not recommended for pregnant or breastfeeding women due to lack of clinical data
Precautions & Warnings
- Does not modify usual rehydration regimens
- Caution with presence of bloody stools and fever
- Not tested in antibiotic-associated diarrhea
- Cautious use in patients with renal or liver impairment
Overdose Effects
- No reported cases of overdose
- In adults, single doses above 2 g have been administered without harmful effects
Therapeutic Class
- Anti-diarrhoeal