Synroid 50 mcg (Tablet)
Unit Price: ৳ 1.60 (1 x 100: ৳ 160.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levothyroxine sodium |
| Company | Beximco pharmaceuticals ltd |
Indications
- Replacement therapy in hypothyroidism of any etiology
- Suppression of Thyroid Stimulating Hormone (TSH) levels for goitres and nodules
- Suppression of goitrogenic effects of other drugs
- Diagnostic aid in suppression tests
Pharmacology
- Contains synthetic Levothyroxine (T4)
- About 30% of T4 is converted to the much more active Triiodothyronine (T3)
- TBG (Thyroxine Binding Globulin) is the major carrier of T4
- Long half-life in the circulation
Dosage & Administration
- Initial starting dose: 25-50 mcg/day
- Gradual increments in dose at 6-8 week intervals
- Adjustments for severe hypothyroidism
- Pediatric Dosage for Newborns and Infants
Interaction
- Concurrent use with tri/tetracyclic antidepressants
- Administration with sertraline
- Addition to antidiabetic or insulin therapy
- Impact on serum digitalis glycoside levels
Contraindications
- Untreated subclinical or overt Thyrotoxicosis
- Acute Myocardial Infarction
- Uncorrected Adrenal failure
Side Effects
- Fatigue, increased appetite, weight loss
- Headache, hyperactivity, nervousness
- Tremors, muscle weakness
- Palpitations, tachycardia, arrhythmias
Pregnancy & Lactation
- Pregnancy Category A
- Increased Levothyroxine requirements during pregnancy
- Minimal excretion in human milk
Precautions & Warnings
- Adrenocortical insufficiency in pituitary gland function
- Careful dosing in patients with cardiovascular disease
- Adjustment of the dosage with marked change of body weight
- Monitoring blood levels of T3 and T4
Overdose Effects
- Signs and symptoms of hyperthyroidism
- Dose reduction or temporary discontinuation if signs appear
- Symptomatic treatment
Therapeutic Class
- Thyroid drugs & hormone
Storage Conditions
- Store below 30°C and dry place
- Protect from light
- Keep out of the reach of children