Mixtard 50 50%+50% in 100 IU/ml (SC Injection)

3 ml penfill: ৳ 460.00 (5's pack: ৳ 2,300.00)

Medicine Details

Category Details
Generic Regular insulin human isophane insulin human
Company Eskayef pharmaceuticals ltd
Also available as
Mixtard 30 30 70 injection

Indications

  • Type 1 Diabetes Mellitus
  • Type 2 Diabetes Mellitus

Composition

  • Insulin Types:
    • Insulin Human R 40 IU/ml
    • Insulin Human R 100 IU/ml
    • Insulin Human N 40 IU/ml
    • Insulin Human N 100 IU/ml
    • Insulin Human 30/70 40 IU/ml
    • Insulin Human 30/70 100 IU/ml
    • Insulin Human 50/50 100 IU/ml
  • Concentration:
    • 40 IU/ml
    • 100 IU/ml
  • Insulin Human Content:
    • Insulin Human (rDNA) USP 40 IU
    • Insulin Human (rDNA) USP 100 IU
  • Insulin Functions:
    • Soluble Insulin Human (Regular)
    • Isophane Insulin Human
    • 30% Soluble Insulin Human (Regular) and 70% Isophane Insulin Human
    • 50% Soluble Insulin Human (Regular) and 50% Isophane Insulin Human

Pharmacology

  • Regulates glucose metabolism
  • Stimulates glucose uptake by liver, muscles, and fat tissue
  • Accelerates glycogen storage
  • Inhibits gluconeogenesis

Dosage

  • Administration Range: 0.5-1.0 IU/kg for type 1 diabetics
  • Variations:
    • Prepubertal vs insulin-resistant patients
  • Initial Dosages for Type 2 Diabetics: 0.3-0.6 IU/kg/day

Administration

  • Preparation:
    • Clean hands
    • Mix solution
    • Check appearance
    • Draw correct dose
    • Inject subcutaneously
  • Injection Site:
    • Upper arm
    • Thigh
    • Buttock
    • Abdomen
  • Instructions:
    • Cleanse skin
    • Puncture at 45° angle
    • Apply gentle pressure after injection

Interaction

  • Increase in Insulin Amount:
    • Oral contraceptive drug
    • Adrenal cortical hormone
    • Thyroid hormone
  • Decrease in Insulin Amount:
    • Hypoglycemic drugs
    • Salicylate
    • Sulfanilamide
    • Anti-depressants

Contraindications

  • Hypoglycemia
  • Allergic reaction to insulin or excipients

Side Effects

  • Hypoglycemia
  • Allergic reaction
  • Redness
  • Swelling
  • Itching

Pregnancy & Lactation

  • No restrictions during pregnancy
  • No risk to baby during nursing

Precautions & Warnings

  • Inadequate dosing may lead to hyperglycemia
  • High insulin dose may cause hypoglycemia
  • Meal omission may lead to hypoglycemia

Overdose Effects

  • Excessive insulin use may lead to hypoglycemia
  • Immediate treatment needed for hypoglycemia

Therapeutic Class

Medium Acting Insulin

Storage Conditions

  • Refrigeration: 2-8°C
  • Avoidance:
    • Freezing
    • Heat
    • Light
  • Unrefrigerated Use: Kept under room temperature for a month

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