Emox-C 250 mg+125 mg (Tablet)

Unit Price: ৳ 20.00 (18's pack: ৳ 360.00)

Medicine Details

Category	Details
Generic	Amoxicillin clavulanic acid
Company	Edruc limited
Also available as	Emox c 500 mg tablet

Indications

Upper respiratory tract infections
Lower respiratory tract infections
Genito-urinary tract infections
Skin and soft tissue infections
Bone and joint infections
Other infections

Composition

375 mg tablet
625 mg tablet
1 gm tablet
Powder for Suspension
Powder for Suspension (Forte)
1.2 gm Injection
0.6 gm injection

Pharmacology

Pharmacodynamic properties: Bactericidal activity against Gram-positive & Gram-negative microorganisms
Pharmacokinetic properties: Closely matched pharmacokinetics of Amoxicillin and Clavulanic Acid

Dosage

Tablet dosage for adults and children over 12 years
Suspension dosage for children
Forte suspension dosage for recommended daily dosage
IV Injection dosage for adults and children

Administration

Oral dosage form can be taken without regard to meals; IV injection is not suitable for intramuscular or subcutaneous administration

Interaction

Prolongation of bleeding time and prothrombin time
Reduced efficacy of oral contraceptives
Concomitant use of allopurinol

Contraindications

History of Penicillin hypersensitivity
Cross-sensitivity with other beta-lactam antibiotics
Previous history of Co-amoxiclav or Penicillin-associated cholestatic jaundice

Side Effects

Diarrhoea
Pseudomembranous colitis
Indigestion
Nausea
Vomiting
Candidiasis
Hepatitis
Cholestatic jaundice
Urticarial rashes
Erythematous rashes
Angioedema
Anaphylaxis

Pregnancy & Lactation

No teratogenic effect in animal studies
Limited human pregnancy use
Trace quantities in breast milk

Precautions & Warnings

Care in patients on anticoagulation therapy
Severe hepatic dysfunction
Renal impairment
High dose administration precautions

Use in Special Populations

Dose adjustment for patients with renal impairment
Administration in hepatic impairment

Overdose Effects

Gastrointestinal symptoms and disturbance of fluid and electrolyte balances

Therapeutic Class

Broad spectrum penicillins

Reconstitution

IV injection reconstitution guidelines

Storage Conditions

Storage temperature and reconstituted suspension guidelines