Bedine 150 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Bengal drugs ltd |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Postoperative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastrointestinal haemorrhage from stress ulcer in seriously ill patients
- Recurrent haemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patients considered to be at risk of acid aspiration
- Reflux oesophagitis
- Episodic dyspepsia
- Prevention of recurrences
Pharmacology
- Competitively blocks histamine at H2-receptors
- Inhibits gastric acid secretion
- Does not affect pepsin secretion
- Does not affect pentagastrin-stimulated intrinsic factor secretion
- Does not affect serum gastrin
Dosage & Administration
- Dosage for duodenal and gastric ulcer: usual dosage is 150 mg twice daily or 300 mg as a single daily dose for 4 to 8 weeks
- Dosage for reflux oesophagitis: 150 mg twice daily or 300 mg at bedtime for up to 8 weeks
- Dosage for Zollinger Ellison syndrome: 150 mg 3 times daily and increased if necessary
- Dosage for episodic dyspepsia: 150 mg twice daily or 300 mg at bedtime for up to 6 weeks
- Children's dosage for peptic ulcer: 2-4 mg/kg twice daily, maximum 300 mg daily
- Dosage for ranitidine IV injection & IV infusion
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Ranitidine excreted in human breast milk
- Caution should be exercised when administered to a nursing mother
Precautions & Warnings
- Should be given in reduced dosage to patients with impaired renal and hepatic function
Use in Special Populations
- Use in elderly patients
Overdose Effects
- Specific in action
- Symptomatic and supportive therapy should be given as appropriate
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Slow IV injection
- Intermittent slow IV infusion
- Continuous IV infusion
- Dilution recommendations for Zollinger-Ellison syndrome or other hypersecretory conditions
Storage Conditions
- Store in a cool and dry place
- Protect from light