Detac 150 mg (Tablet)

Unit Price: ৳ 1.00 (15 x 10: ৳ 150.00)
Strip Price: ৳ 10.00

Medicine Details

Category Details
Generic Ranitidine hydrochloride
Company Desh pharmaceuticals ltd

Indications

  • Treatment of active duodenal ulcer
  • Benign gastric ulcer
  • Ulcer associated with non-steroidal anti-inflammatory agent
  • Post operative stress ulcer
  • Zollinger-Ellison Syndrome
  • Gastroesophageal reflux disease (GERD)
  • Gastro-intestinal hemorrhage from stress ulcer
  • Recurrent hemorrhage in patients with bleeding peptic ulcer
  • Before general anesthesia in patient considered to be at risk of acid aspiration
  • Obstetric patients at risk of acid aspiration

Pharmacology

Competitively blocks histamine at H2-receptors of the gastric parietal cells, inhibiting gastric acid secretion

Dosage & Administration

  • Ranitidine Tablet & Syrup:
    • Duodenal and gastric ulcer: 150 mg twice daily or 300 mg as a single daily dose
    • Reflux oesophagitis: 150 mg twice daily or 300 mg at bedtime
    • Zollinger Ellison syndrome: 150 mg 3 times daily, increased if necessary
    • Episodic dyspepsia: 150 mg twice daily or 300 mg at bedtime
    • Maintenance: 150 mg at night
    • Child (peptic ulcer): 2-4 mg/kg twice daily
  • Ranitidine IV injection & IV Infusion: Dosage and administration instructions for intravenous administration

Interaction

Delayed absorption and increased peak serum concentration with propantheline bromide. May alter absorption of pH-dependent drugs. May reduce bioavailability with antacids

Contraindications

Patients hypersensitive to Ranitidine

Side Effects

  • Altered bowel habit
  • Dizziness
  • Rash
  • Tiredness
  • Reversible confusional states
  • Headache
  • Decreased blood counts
  • Muscle or joint pain

Pregnancy & Lactation

  • Pregnancy: Ranitidine crosses the placenta. Should only be used if considered essential
  • Lactation: Caution should be exercised when administered to a nursing mother

Precautions & Warnings

Should be given in reduced dosage to patients with impaired renal and hepatic function

Use in Special Populations

Use in elderly patients

Overdose Effects

No particular problems expected following overdosage

Therapeutic Class

H2 receptor antagonist

Reconstitution

Instructions for reconstituting Detac for different administration methods

Storage Conditions

Store in a cool and dry place, protect from light

Related Brands