Voricon 200 mg/5 ml (Powder for Suspension)

40 ml bottle: ৳ 1,000.00

Medicine Details

Title

  • Voriconazole 200mg tablet
  • Voriconazole Powder for Suspension

Category

  • Antifungal Medication
  • Prescription Drug

Description

  • Used for the treatment of invasive aspergillosis
  • Indicated for candidemia and disseminated candidiasis
  • Effective against esophageal candidiasis
  • Treats serious infections caused by specific fungi
  • Suitable for patients intolerant of other therapy

Age Group

  • 12 years and older

Pharmacology

  • Binds and inhibits ergosterol synthesis
  • Inhibits CYP450-dependent 14-alpha sterol demethylase
  • Depletes ergosterol in fungal cell membrane

Dosage Forms

  • Tablet
  • Powder for Suspension
  • Injection

Dosage Instructions

  • To be taken at least one hour before or after a meal
  • Different dosage for body weight above and below 40 kg
  • Loading and maintenance dose regimens for different infections

Interaction

  • Interacts with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
  • May increase concentrations and activity of other drugs
  • Alters dosage when co-administered with specific drugs

Contraindications

  • Hypersensitivity to voriconazole or its components
  • Co-administration with specific drugs due to risk of adverse reactions

Side Effects

  • Abdominal pain
  • Anemia
  • Blurred vision
  • Headache
  • Chest pain
  • Nausea
  • Diarrhea

Pregnancy Use

  • Use during pregnancy only if potential benefit justifies risk to fetus
  • No adequate and well-controlled studies available

Precautions Warnings

  • Long-term exposure requires careful assessment of benefit-risk balance
  • Reported association with squamous cell carcinoma of the skin for long-term treatment
  • Efficacy not established in children under 12 years of age

Overdose Effects

  • No available data on overdose effects

Therapeutic Class

  • Antifungal preparation

Reconstitution Instructions

  • Shake well before adding water
  • Specific instructions for suspension reconstitution and storage

Storage Conditions

  • Store in a dry place
  • Keep out of reach of children
  • Store at specific temperatures as indicated

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