Eucon 150 mg (Tablet)
Unit Price: ৳ 1.90 (10 x 10: ৳ 190.00)
Strip Price: ৳ 19.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
- Recurrent haemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patient considered to be at risk of acid aspiration particularly obstetric patients
Pharmacology
- Competitively blocks histamine at H2-receptors of the gastric parietal cells
- Inhibits gastric acid secretion
- Does not affect pepsin secretion, pentagastrin-stimulated intrinsic factor secretion or serum gastrin
Dosage & Administration
- Usual dosage of 150 mg twice daily or 300 mg as a single daily dose for 4 to 8 weeks
- Dosage for reflux oesophagitis, Zollinger Ellison syndrome, episodic dyspepsia, and maintenance
- Dosage for children with peptic ulcers
- Dosage for IV injection & infusion in various conditions
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Should be used during pregnancy if considered essential
- Excreted in human breast milk
- Caution in nursing mothers
Precautions & Warnings
- Should be given in reduced dosage to patients with impaired renal and hepatic function
Use in Special Populations
- Use in elderly patients - similar ulcer healing rates as younger patients
- No difference in adverse effects between elderly and younger patients
Overdose Effects
- No particular problems expected following overdosage
- Symptomatic and supportive therapy recommended
- May be removed from plasma by haemodialysis
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Instructions for slow IV injection, intermittent slow IV infusion, and continuous IV infusion
- Specific instructions for patients with hypersecretory conditions
Storage Conditions
- Store in a cool and dry place
- Protect from light