Doctrim 800 mg+160 mg (Tablet)

Unit Price: ৳ 1.74 (100's pack: ৳ 174.00)

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Doctors chemical works ltd
Also available as	Doctrim 200 mg suspension Doctrim 400 mg tablet

Title

Cotrimoxazole Tablet

Description

Cotrimoxazole is a bactericidal medication with broad-spectrum activity against various bacterial infections. It consists of a combination of Trimethoprim and Sulphamethoxazole and is used to treat respiratory tract infections, genito-urinary tract infections, gastro-intestinal tract infections, and more. It is important to consider contraindications, side effects, dosage, storage conditions, and therapeutic class when using this medication.

DosageInstructions

For mild to moderate infections: 1-2 tablets twice daily
For severe infections: 1.5-2 tablets twice daily
Long term therapy (>14 days): 0.5-1 tablet twice daily

Indications

Respiratory tract infections
Genito-urinary tract infections
Gastro-intestinal tract infections
Osteomyelitis
Skin infections
Septicaemia
Dysentery
Cholera

ModeOfAction

Cotrimoxazole exerts its bactericidal action by the sequential blockade of two bacterial enzyme systems in the biosynthesis of folinic acid in microorganisms.

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anemia due to folate deficiency
Liver parenchymal damage
Severe renal insufficiency
Glucose 6-phosphate dehydrogenase deficiency

SideEffects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting

PregnancyAndLactation

Avoid during pregnancy and nursing period due to potential adverse effects on the baby.

PrecautionsAndWarnings

Prolonged full-dose treatment has the risk of macrocytic anemia. Caution with diabetic patients receiving sulphonylurea drug.