Hi Floxin (200 mg+40 mg)/5 ml (Oral Suspension)

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Hudson pharmaceuticals ltd
Also available as	Seftrim ds 800 mg tablet Seftrim 200 mg suspension Hi floxin 400 mg tablet

Product Title

Cotrimoxazole Tablet

Categories

Antibiotics
Anti-infective Agents
Sulfonamides

Description

Broad-spectrum bactericidal activity
Effective against various bacterial and protozoal infections

Active Ingredients

Trimethoprim
Sulphamethoxazole

Dosage Form

Tablet

Indications

Respiratory tract infections
Genito-urinary tract infections
Gastro-intestinal tract infections
Chronic osteomyelitis
Skin infections
Septicaemia
Bacillary dysentery
Cholera
Nocardiosis
Mycetoma

Mode of Action

Sequential blockade of bacterial enzyme systems in the biosynthesis of folinic acid

Dosage & Administration

Tablet Over 12 years:
- Mild to moderate infections: 1-2 tablets twice daily
- Severe infections: 1.5-2 tablets twice daily
- Long-term therapy (>14 days): 0.5-1 tablet twice daily
- Gonorrhoea: 2 tablets every 12 hours for two days or 2.5 tablets followed by a further dose of 2.5 tablets after 8 hours
Suspension Under 12 years:
- 6-12 years: 2 teaspoonful twice daily
- 6 months-5 years: 1 teaspoonful twice daily
- 6 weeks-6 months: 0.5 teaspoonful twice daily

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anaemia due to folate deficiency
Liver parenchymal damage
Blood dyscrasia
Severe renal insufficiency

Side Effects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting

Pregnancy & Lactation

Not recommended due to potential risk to the fetus and nursing infant

Precautions & Warnings

Risk of macrocytic anaemia
Avoid in diabetic patients receiving sulphonylurea drug

Therapeutic Class

Antidiarrheal Antimicrobial drugs
Sulphonamides & Trimethoprim

Storage Conditions

Below 30°C, away from light & moisture

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