Semotrim 400 mg+80 mg (Tablet)

Unit Price: ৳ 2.06 (100's pack: ৳ 206.00)

Medicine Details

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Skin infections
  • Septicaemia
  • Dysentery
  • Cholera

Pharmacology

Broad spectrum bactericidal activity against a wide range of gram-positive & gram-negative bacteria and some protozoa

Dosage & Administration

  • Cotrimoxazole double strength tablet:
    • Over 12 years:
      • For mild to moderate infections: 1 tablet twice daily
      • For severe infections: 1.5 tablets twice daily
      • Long term therapy (>14 days): 0.5 tablet twice daily
      • Gonorrhoea: 2 tablets every 12 hours for two days or 2.5 tablets followed by a further dose of 2.5 tablets after 8 hours
  • Cotrimoxazole tablet:
    • Over 12 years:
      • For mild to moderate infections: 2 tablets twice daily
      • For severe infections: 2 tablets thrice daily
      • Long term therapy (>14 days): 1 tablet twice daily
  • Cotrimoxazole suspension:
    • Under 12 years:
      • 6-12 years: 2 teaspoonful twice daily
      • 6 month-5 years: 1 teaspoonful twice daily
      • 6 weeks-6 months: 0.5 teaspoonful twice daily

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

Avoid during pregnancy and nursing period due to potential risks

Precautions & Warnings

  • Risk of macrocytic anaemia
  • Potential potentiation of action of sulphonylurea in diabetic patients

Therapeutic Class

Anti-diarrhoeal Antimicrobial drugs, Sulphonamides & Trimethoprim

Storage Conditions

Keep below 30°C temperature, away from light & moisture, and out of the reach of children

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