Sitrim 400 mg+80 mg (Tablet)

Unit Price: ৳ 2.01 (10 x 10: ৳ 200.75)
Strip Price: ৳ 20.08

Medicine Details

Title

  • Cotrimoxazole Double Strength Tablet

Categories

  • Antibacterial
  • Antimicrobial
  • Sulphonamide
  • Trimethoprim
  • Therapeutic Drug
  • Prescription Medication

Description

  • Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
  • Effective treatment for respiratory tract infections, genito-urinary tract infections, gastrointestinal tract infections, and other infections
  • Broad spectrum bactericidal activity
  • Contains Trimethoprim and Sulphamethoxazole in a 1:5 combination
  • Sequential blockade of two bacterial enzyme systems in the biosynthesis of folinic acid
  • Dosage and administration instructions for mild to severe infections, long-term therapy, and gonorrhea treatment
  • Contraindications for hypersensitivity to trimethoprim or sulphonamides, megaloblastic anemia, liver parenchymal damage, blood dyscrasia, severe renal insufficiency, and glucose 6-phosphate dehydrogenase deficiency
  • Rare side effects such as crystalluria, allergic reactions, haemolysis, thrombocytopenia, neutropenia, agranulocytosis
  • Less serious side effects include malaise, headache, nausea, vomiting
  • Sulphonamides pass the placenta and are excreted in breast milk, posing risks during pregnancy and nursing
  • Prolonged full dose treatment may be associated with the risk of macrocytic anemia
  • Potentiation of action of sulphonylurea in diabetic patients
  • Belongs to the therapeutic class of Anti-diarrhoeal Antimicrobial drugs, Sulphonamides & Trimethoprim
  • Storage recommendations: Keep below 30°C, away from light and moisture, out of the reach of children

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastrointestinal tract infections
  • Other infections such as osteomyelitis, brucellosis, skin infections, septicaemia, bacillary dysentery, and more

Mode of Action

  • Broad spectrum bactericidal activity against gram-positive & gram-negative bacteria and some protozoa

Dosage & Administration

  • Dosage instructions for Cotrimoxazole double strength tablet, tablet, and suspension for different age groups
  • Directions for mild to severe infections, long-term therapy, and gonorrhea treatment

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anemia
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Rare side effects such as crystalluria, allergic reactions, haemolysis, thrombocytopenia, neutropenia, agranulocytosis
  • Less serious side effects include malaise, headache, nausea, vomiting

Pregnancy & Lactation

  • Sulphonamides pass the placenta and are excreted in breast milk, posing risks during pregnancy and nursing

Precautions & Warnings

  • Prolonged treatment risk of macrocytic anemia
  • Potential potentiation of action of sulphonylurea in diabetic patients

Therapeutic Class

  • Anti-diarrhoeal Antimicrobial drugs
  • Sulphonamides & Trimethoprim

Storage Conditions

  • Keep below 30°C, away from light and moisture, out of the reach of children

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