Inseac 150 mg (Tablet)
Unit Price: ৳ 2.50 (15 x 10: ৳ 375.00)
Strip Price: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Ibn sina pharmaceuticals ltd |
Indications
- Active duodenal ulcer treatment
- Benign gastric ulcer treatment
- Ulcer prevention with NSAID use
- Post-operative stress ulcer treatment
- Zollinger-Ellison Syndrome treatment
- GERD (gastroesophageal reflux disease) treatment
- Ulcer prevention in seriously ill patients
- Recurrent bleeding peptic ulcer treatment
- Preoperative acid aspiration risk prevention
Pharmacology
Ranitidine competitively blocks histamine at H2-receptors of gastric parietal cells, inhibiting gastric acid secretion without affecting pepsin secretion, intrinsic factor secretion, or serum gastrin.
Dosage & Administration
- Ranitidine Tablet & Syrup:
- Duodenal and gastric ulcer: 150 mg twice daily for 4-8 weeks
- Reflux esophagitis: 150 mg twice daily for up to 8 weeks
- Zollinger-Ellison syndrome: 150 mg 3 times daily, up to 6 g daily
- Episodic dyspepsia: 150 mg twice daily for up to 6 weeks
- Maintenance: 150 mg at night for preventing recurrences
- Child (peptic ulcer): 2-4 mg/kg twice daily, maximum 300 mg daily
- Ranitidine IV injection & IV Infusion: Doses vary depending on condition, slow IV injection or infusion may be administered every six to eight hours, and maintenance doses may be given until oral feeding commences. Pediatric use is also specified.
Interaction
Inseac may interact with propantheline bromide, coumarin anticoagulants, theophylline, diazepam, propranolol, pH-dependent drugs, and antacids.
Contraindications
Hypersensitivity to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain (rare)
Pregnancy & Lactation
- Pregnancy: Ranitidine crosses the placenta, should be used during pregnancy only if considered essential
- Lactation: Ranitidine is excreted in human breast milk, caution is advised during nursing
Precautions & Warnings
Inseac should be given in reduced dosage to patients with impaired renal and hepatic function.
Use in Special Populations
Elderly patients' ulcer healing rates are similar to younger patients without increased adverse effects.
Overdose Effects
No specific problems expected, symptomatic and supportive therapy as appropriate.
Therapeutic Class
H2 receptor antagonist
Reconstitution
- Slow IV inj: Inseac 50 mg diluted to a concentration ≤2.5 mg/mL with specific solutions
- Intermittent slow IV infusion: Inseac 50 mg diluted to a concentration ≤0.5 mg/mL with specific solutions
- Continuous IV infusion: Inseac 150 mg diluted in 250 mL of specific solutions
- Special conditions: Inseac should be diluted to specific concentrations in certain conditions
Storage Conditions
Store in a cool and dry place, protect from light.