Xolamid 1% (Ophthalmic Suspension)

5 ml drop: ৳ 501.50

Medicine Details

Category	Details
Generic	Brinzolamide
Company	Opsonin pharma ltd

Indications

Treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma

Pharmacology

Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion
Reduction in intraocular pressure (IOP)

Dosage & Administration

Shake well before use
Insert 1 drop in the affected eye(s) three times daily
Concomitant use with other topical ophthalmic products
Pediatric use: 1 drop in the affected eye(s) 2 times daily (4 weeks to 5 years age)
Geriatric use: No overall differences in safety or effectiveness observed between elderly and younger patients

Interaction

Rare instances of drug interactions with high-dose salicylate therapy in patients treated with oral carbonic anhydrase inhibitors

Contraindications

Hypersensitivity to any component of this product

Side Effects

Blurred vision
Bitter, sour, or unusual taste
Blepharitis
Dermatitis
Dry eye
Foreign body sensation
Headache
Hyperemia
Ocular discharge
Ocular discomfort
Ocular keratitis
Ocular pain
Ocular pruritus
Allergic reactions
Alopecia
Chest pain
Conjunctivitis
Dizziness
Dry mouth
Dyspnea
Dyspepsia
Eye fatigue
Hypertonia
Keratoconjunctivitis
Lid margin crusting or sticky sensation
Nausea
Pharyngitis
Tearing
Urticaria

Pregnancy & Lactation

Pregnancy Category C
No adequate and well-controlled studies in pregnant women
Use during pregnancy only if potential benefit justifies potential risk to the fetus
Use only if potential benefit justifies potential risk to the baby

Precautions & Warnings

Sulfonamide drug
Absorbed systemically
Adverse reactions attributable to sulfonamides may occur
Fatalities rarely occurred due to severe reactions to sulfonamides
Sensitization may occur upon re-administration of a sulfonamide
Discontinue use if serious reactions or hypersensitivity occur
Not recommended in renal impairment patients
Use with caution in patients with hepatic impairment

Overdose Effects

Electrolyte imbalance
Development of an acidosis state
Possible nervous system effects following oral administration of an overdose
Monitor serum electrolyte levels (particularly potassium) and blood pH levels

Therapeutic Class

Drugs for miotics and glaucoma

Storage Conditions

Store at room temperature
Protect from light
Do not touch dropper tip to any surface
Contents should not be used more than four weeks after first opening of the bottle
Protect from freezing

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