Zolaren 1% (Ophthalmic Suspension)

5 ml drop: ৳ 500.00

Medicine Details

Category Details
Generic Brinzolamide
Company Incepta pharmaceuticals ltd

Indications

  • Treatment of elevated intraocular pressure in patients with ocular hypertension
  • Treatment of elevated intraocular pressure in patients with open-angle glaucoma

Pharmacology

  • Inhibition of carbonic anhydrase in the ciliary processes of the eye
  • Decreases aqueous humor secretion
  • Reduction in intraocular pressure

Dosage & Administration

  • Shake well before use
  • Insert 1 drop in the affected eye(s) three times daily
  • Pediatric Use: One drop in the affected eye(s) 2 times daily in pediatric patient (4 weeks to 5 years age)
  • Geriatric Use: No overall differences in safety or effectiveness observed between elderly and younger patients
  • May be used concomitantly with other topical ophthalmic products to lower intraocular pressure
  • If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart

Interaction

  • Possible drug interactions with high-dose salicylate therapy in patients treated with oral carbonic anhydrase inhibitors

Contraindications

  • Hypersensitivity to any component of this product

Side Effects

  • Blurred vision
  • Bitter, sour or unusual taste
  • Blepharitis
  • Dermatitis
  • Dry eye
  • Foreign body sensation
  • Headache
  • Hyperemia
  • Ocular discharge
  • Ocular discomfort
  • Ocular keratitis
  • Ocular pain
  • Ocular pruritus
  • Allergic reactions
  • Alopecia
  • Chest pain
  • Conjunctivitis
  • Dizziness
  • Dry mouth
  • Dyspnea
  • Dyspepsia
  • Eye fatigue
  • Hypertonia
  • Keratoconjunctivitis
  • Lid margin crusting or sticky sensation
  • Nausea
  • Pharyngitis
  • Tearing
  • Urticaria

Pregnancy & Lactation

  • Pregnancy Category C
  • Use during pregnancy only if the potential benefit justifies the potential risk to the fetus

Precautions & Warnings

  • Zolaren is a sulfonamide and absorbed systemically
  • Potential serious adverse reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias
  • Sensitization may occur with repeated administration
  • Discontinue use if serious reactions or hypersensitivity occur
  • Not recommended in renal impairment patients
  • Use with caution in patients with hepatic impairment

Overdose Effects

  • Electrolyte imbalance
  • Development of an acidosis state
  • Possible nervous system effects

Therapeutic Class

  • Drugs for miotics and glaucoma

Storage Conditions

  • Store at room temperature & protect from light
  • Do not touch dropper tip to any surface
  • Contents should not be used more than four weeks after first opening of the bottle
  • Protect from freezing

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