Esotor 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related Dyspepsia
  • Treatment of duodenal and gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Absorption through enteric-coated pellet formulation
  • Metabolized in the liver by cytochrome P450 enzyme system
  • Extensive metabolism leading to inactive metabolites in urine and feces

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Different dosages for different indications
  • Dosage forms for pediatric and adult patients
  • Dosage for risk reduction of rebleeding of gastric or duodenal ulcers following therapeutic endoscopy

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension administration instructions
  • IV Injection preparation and administration instructions

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • No clinically relevant interactions with certain drugs
  • Potential interference with absorption of other drugs

Contraindications

  • Hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion of esomeprazole in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude presence of gastric malignancy
  • Administration instructions for patients experiencing difficulty swallowing capsules
  • Use of antacids while taking Esotor

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy observed in elderly patients
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Expected pharmacokinetics in patients with renal impairment

Overdose Effects

  • Lethal dose in rats
  • Signs of acute toxicity

Storage Conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Commonly Asked Questions

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