Esotor 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Esomeprazole
Company Nipro jmi pharma ltd
Also available as
Esotor 20 mg capsule Esotor 40 mg capsule Esotor 20 mg tablet

Indications

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment for Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Treatment for Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase in the gastric parietal cell
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Peak plasma levels (Cmax) occur at approximately 1.5 hours (Tmax)
  • Extensively metabolized in the liver by the cytochrome P450 (CYP) enzyme system

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Various dosage regimens for different conditions
  • Specific dosages for adults and pediatric patients

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension administration instructions
  • IV Injection preparation and administration guidelines

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • Inhibition of CYP2C19
  • Potential interference with absorption of certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Frequently occurring adverse events include headache, diarrhea, nausea, and abdominal pain
  • No significant difference in adverse events during maintenance treatment compared to short-term treatment

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies have shown no teratogenic effects
  • Excretion of esomeprazole in milk not studied
  • Discontinuation of breastfeeding if essential use of esomeprazole

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Specific instructions for taking capsules for patients with difficulty swallowing

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy between elderly and younger individuals

Overdose Effects

  • Signs of acute toxicity in rats
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure: Image available

Common Questions about Esotor 40 mg Tablet

  • Proton pump inhibitor for reducing stomach acid production
  • Used for treating GERD, ulcers, and other conditions
  • List of common side effects
  • Guidelines for pregnant or breastfeeding individuals
  • Onset of action and quick tips for usage

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