Neoceptin R 75 mg/5 ml (Syrup)

100 ml bottle: ৳ 50.00

Medicine Details

Indications

  • Treatment of active duodenal ulcer
  • Benign gastric ulcer
  • Prevention of ulcer associated with non-steroidal anti-inflammatory agent
  • Post operative stress ulcer
  • Zollinger-Ellison Syndrome
  • Gastroesophageal reflux disease (GERD)
  • Gastro-intestinal haemorrhage treatment
  • Recurrent haemorrhage treatment
  • Prevention of acid aspiration risk
  • Maintenance for preventing recurrences

Pharmacology

  • Competitively blocks histamine at H2-receptors
  • Inhibits gastric acid secretion
  • Does not affect pepsin secretion or serum gastrin

Dosage & Administration

  • 150 mg twice daily for duodenal and gastric ulcer
  • 300 mg as a single daily dose at night for 4 to 8 weeks
  • 150 mg twice daily for reflux esophagitis
  • 150 mg 3 times daily for Zollinger Ellison syndrome
  • 150 mg twice daily for episodic dyspepsia
  • Maintenance dosage at 150 mg
  • Parenteral administration options for stress ulceration and peptic ulceration
  • Injectable dosage for children based on weight
  • Dosage adjustments for specific medical conditions

Interaction

  • Delayed absorption with propantheline bromide
  • Minimally inhibits hepatic metabolism of certain drugs
  • Alters absorption of pH-dependent drugs
  • Reduces bioavailability with antacids

Contraindications

  • Hypersensitivity to Ranitidine

Side Effects

  • Altered bowel habit
  • Dizziness
  • Rash
  • Tiredness
  • Confusional states
  • Headache
  • Decreased blood counts
  • Muscle or joint pain

Pregnancy & Lactation

  • Crosses placenta
  • Caution during pregnancy
  • Excreted in human breast milk
  • Caution during lactation

Precautions & Warnings

  • Reduced dosage for impaired renal and hepatic function

Use in Special Populations

  • Elderly patients - similar ulcer healing rates observed
  • No difference in adverse effects in elderly patients

Overdose Effects

  • Specific action minimizes problems with overdosage
  • Symptomatic and supportive therapy recommended
  • Potential for removal by hemodialysis

Therapeutic Class

  • H2 receptor antagonist

Reconstitution

  • Slow IV injection guidelines
  • Intermittent slow IV infusion recommendations
  • Continuous IV infusion instructions
  • Dilution guidelines for specific medical conditions

Storage Conditions

  • Store in a cool and dry place
  • Protect from light

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