Nixon 1 gm/vial (IM Injection)

1 gm vial: ৳ 220.66

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Nipro jmi pharma ltd
Also available as
Nixon 250 mg injection Nixon 250 mg injection Nixon 500 mg injection Nixon 500 mg injection Nixon 1 gm injection Nixon 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
  • Interferes with the synthesis of the bacterial cell wall
  • High degree of stability in the presence of beta lactamases
  • Long plasma elimination half-life of about 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum adult dose: 4 gm/day
  • Infants and Children dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Maximum pediatric dose: 2 gm/day
  • Duration of therapy: 4 to 14 days

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Administered over 2-4 minutes for intramuscular or intravenous injection
  • Tubing infusion over a period of 30 minutes at concentration between 10 mg/mL and 40 mg/mL
  • Patient tolerance test should be checked by administration of a test dose

Interaction

  • No reported drug interactions

Contraindications

  • History of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution when administered to a lactating mother

Precautions & Warnings

  • Anaphylactic shock
  • Shadows suggesting sludge in the gallbladder
  • Blood picture should be checked at regular intervals

Use in Special Populations

  • Not to be given to premature neonates
  • Avoid use in newborns up to 28 days of age

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Away from light and moisture
  • Keep out of the reach of children

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