Xinarox 750 mg/vial (IM/IV Injection)
750 mg vial: ৳ 125.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Nipro jmi pharma ltd |
| Also available as |
Product Title
- Xinarox Tablet
Categories
- Medicine
- Antibiotics
- Infection Treatment
Description
- Xinarox Tablet is indicated for the treatment of infections caused by sensitive bacteria such as pharyngitis/tonsillitis, acute bacterial otitis media, acute bacterial maxillary sinusitis, lower respiratory tract infections, skin and skin-structure infections, urinary tract infections, bone and joint infections, gonorrhoea, early lyme disease, and more.
Dosage Forms Available
- Tablet
- Suspension
- Intramuscular Injection
- Intravenous Injection
Active Ingredient
- Cefuroxime
Pharmacology
- Cefuroxime is a well-characterized and effective antibacterial agent, which has broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains. Cefuroxime has good stability to bacterial β-lactamase and consequently, is active against many ampicillin-resistant and amoxycillin-resistant strains.
Dosage Guidelines
- Dosage varies for different age groups and types of infections.
Storage Conditions
- Store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children.
Administration Recommendation
- The use of freshly reconstituted solution is recommended. However, it maintains potency for at least 24 hours at room temperature or 48 hours at 5°C.
Interaction Info
- No potentially hazardous interactions have been reported.
Contraindications
- Cefuroxime is contraindicated in patients with known allergy to Cephalosporins.
Side Effects
- Adverse effects to Xinarox have occurred infrequently and have been generally mild and transient in nature.
Pregnancy Lactation Info
- US FDA pregnancy category of Cefuroxime is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Cefuroxime has been shown to be excreted in human milk. So, caution should be exercised when Cefuroxime is administered to a nursing woman.
Precautions Warnings
- Xinarox should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis.
Therapeutic Class
- Second generation Cephalosporins
Reconstitution Guidelines
- For 750 mg intramuscular injection: Add 3 ml water for injection to vial and then shake gently for dispersion. For 750 mg intravenous injection: Add 8 ml water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period. For 1.5 g intravenous injection: Add 16 ml Water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period.
Usability Instructions
- Cefuroxime dosage should be as prescribed by a healthcare professional.
Storage Recommendation
- Store the product below 30°C, away from light & moisture.
Allergy Information
- Patients with known allergy to Cephalosporins should avoid using this medication.
Excretion Info
- Cefuroxime has been shown to be excreted in human milk.
Drug Classification
- Cefuroxime belongs to the class of Second generation Cephalosporins.
Infection Targets
- Xinarox is effective against a wide range of sensitive bacteria causing various infections such as pharyngitis, otitis media, maxillary sinusitis, pneumonia, bronchitis, skin and skin-structure infections, urinary tract infections, and more.
Diverse Dosage Options
- Xinarox offers diverse dosage options based on age groups and types of infections.
Stability At Varying Temperatures
- Xinarox maintains potency for at least 24 hours at room temperature or 48 hours at 5°C after reconstitution.
Mild Adverse Effects
- Adverse effects to Xinarox have been generally mild and transient in nature.
Pregnancy Use Caution
- Caution should be exercised when Cefuroxime is used during pregnancy or administered to a nursing woman.
Cross Reactions Possible
- Cephalosporin antibiotics may be given safely to patients who are hypersensitive to penicillin although cross reactions have been reported.
Dosage Adjustments
- Dosage may need to be adjusted for patients receiving concurrent treatment with potent diuretics or those with a history of colitis.
Infection Resistance Potential
- Prolonged use may result in the overgrowth of non-susceptible organisms such as Candida.
Caution For Concurrent Medication
- Caution should be exercised for patients receiving concurrent treatment with potent diuretics.
Injection Administration Guidelines
- Intramuscular and intravenous injection guidelines are provided for different dosages.
Efficacy Against Resistant Strains
- Cefuroxime is active against many ampicillin-resistant and amoxycillin-resistant strains.
Potential Use In Pediatrics
- Xinarox may be suitable for pediatric patients based on the recommended dosage options.
Potential Use In Adults
- Xinarox is indicated for use in adolescents and adults for the treatment of various infections.
Usability Suggestion
- For optimal effectiveness, Cefuroxime dosage should be as prescribed by a healthcare professional.
Administration Suggestion
- The use of freshly reconstituted solution is recommended for administration.
Storage Guideline
- Store Xinarox in a cool, dry place below 30°C, away from light & moisture.
Best Prescribed By Professionals
- Xinarox dosage should be prescribed by healthcare professionals based on the specific infection and patient characteristics.
Antibiotic Efficacy
- Xinarox is an effective antibacterial agent with broad-spectrum bactericidal activity against a wide range of common pathogens.
Infection Specific Treatment
- Xinarox offers specific treatment options for various infections such as pharyngitis, otitis media, maxillary sinusitis, pneumonia, bronchitis, skin and skin-structure infections, urinary tract infections, and more.