Xinarox 1.5 gm/vial (IV Injection)

1.5 gm vial: ৳ 200.00

Medicine Details

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae
  • Acute bacterial maxillary sinusitis caused by Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae
  • Skin and skin-structure infections caused by Staphylococcus aureus
  • Urinary tract infections caused by E.coli
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi

Pharmacology

Cefuroxime has broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains.

Dosage

  • Dosage varies for different conditions and age groups. It includes both tablet/suspension and parenteral administration.

Administration

The use of freshly reconstituted solution is recommended. It maintains potency for at least 24 hours at room temperature.

Interaction

No potentially hazardous interactions have been reported.

Contraindications

Cefuroxime is contraindicated in patients with known allergy to Cephalosporins.

Side Effects

  • Adverse effects to Xinarox have occurred infrequently and have been generally mild and transient in nature.
  • Prolonged use may result in the overgrowth of non-susceptible organisms e.g. Candida.

Pregnancy & Lactation

US FDA pregnancy category of Cefuroxime is B. Caution should be exercised when administered to a nursing woman.

Precautions & Warnings

Xinarox should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis.

Therapeutic Class

Second generation Cephalosporins

Reconstitution

  • For 750 mg intramuscular injection: Add 3 ml water for injection to vial and then shake gently for dispersion.
  • For 750 mg intravenous injection: Add 8 ml water for injection to vial and then shake gently for dispersion.
  • For 1.5 g intravenous injection: Add 16 ml Water for injection to vial and then shake gently for dispersion.

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture.

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