Linamet 2.5 mg+500 mg (Tablet)
Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Linagliptin metformin hydrochloride |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Therapeutic Class
- Combination Oral hypoglycemic preparations
Indications
- Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
Pharmacology
- Linagliptin is an inhibitor of DPP-4 enzyme
- Metformin Hydrochloride lowers plasma glucose levels
Dosage & Administration
- Individualized dosage based on effectiveness and tolerability
- Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals
Interaction
- Potential interaction with cationic drugs
- Interaction with carbonic anhydrase inhibitors
- Effects of inducers of P-glycoprotein and CYP3A4 enzymes
- Interactions with drugs affecting glycemic control
Contraindications
- Contraindicated in patients with renal impairment
- Contraindicated in acute or chronic metabolic acidosis
- Contraindicated in hypersensitivity to Linagliptin or Metformin Hydrochloride
Side Effects
- Most common side effects are nasopharyngitis and diarrhea
- Hypoglycemia is more common in patients treated with Linamet and sulfonylureas
Pregnancy & Lactation
- Caution should be exercised when used during pregnancy
- Caution should be exercised when administered to a lactating mother
Precautions & Warnings
- Discontinue in case of lactic acidosis
- Monitor Vitamin B12 levels regularly
Overdose Effects
- Supportive measures in case of overdose
- Removal of unabsorbed material from the gastrointestinal tract
- Clinical monitoring and supportive treatment
- Likelihood of dialysis for Metformin Hydrochloride in overdose cases
Storage Conditions
- Store in a cool & dry place below 30°C
- Protect from light & moisture
- Keep out of the reach of children