Neosetin R 150 mg (Tablet)

Unit Price: ৳ 1.50 (100's pack: ৳ 150.00)

Medicine Details

Category Details
Generic Ranitidine hydrochloride
Company Bristol pharmaceuticals ltd

Indications

  • Treatment of active duodenal ulcer
  • Benign gastric ulcer
  • Prevention of ulcer associated with non-steroidal anti-inflammatory agents
  • Post operative stress ulcer
  • Zollinger-Ellison Syndrome
  • Gastroesophageal reflux disease (GERD)
  • Gastro-intestinal hemorrhage from stress ulcer in seriously ill patient
  • Recurrent hemorrhage in patients with bleeding peptic ulcer
  • Before general anesthesia in patients at risk of acid aspiration, particularly obstetric patients

Pharmacology

Competitively blocks histamine at H2-receptors of the gastric parietal cells, inhibiting gastric acid secretion. Does not affect pepsin secretion, intrinsic factor secretion, or serum gastrin.

Dosage & Administration

  • Ranitidine Tablet & Syrup:
    • 150 mg twice daily for duodenal and gastric ulcer
    • 150 mg twice daily for reflux esophagitis
    • 150 mg 3 times daily for Zollinger-Ellison syndrome
    • 150 mg twice daily for episodic dyspepsia
    • 150 mg at night for maintenance to prevent recurrences
    • 2-4 mg/kg twice daily for children with peptic ulcer
  • Ranitidine IV injection & IV Infusion: Dosage varies based on the indication and patient demographics

Interaction

May affect the absorption and bioavailability of other medications

Contraindications

Hypersensitivity to Ranitidine

Side Effects

  • Altered bowel habit
  • Dizziness
  • Rash
  • Tiredness
  • Reversible confusional states
  • Headache
  • Decreased blood counts
  • Muscle or joint pain

Pregnancy & Lactation

  • Pregnancy: Crosses the placenta, caution advised
  • Lactation: Excreted in human breast milk, caution advised

Precautions & Warnings

Reduced dosage recommended for patients with impaired renal and hepatic function

Use in Special Populations

Similar ulcer healing rates in elderly patients; no significant difference in adverse effects

Overdose Effects

Expected to have minimal problems; symptomatic and supportive therapy recommended if needed

Therapeutic Class

H2 receptor antagonist

Reconstitution

Instructions for reconstitution of Neosetin R for intravenous usage

Storage Conditions

Store in a cool and dry place, protect from light

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