Ligazid M 2.5 mg+500 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Linagliptin metformin hydrochloride
Company Eskayef pharmaceuticals ltd
Also available as
Ligazid m 25 mg tablet Ligazid m 25 mg tablet Ligazid mx 5 mg tablet

Title

  • Ligazid M Tablet

Categories

  • Medicine
  • Diabetes Management
  • Oral Hypoglycemic Preparations

Description

  • Adjunct to diet and exercise for glycemic control in type 2 diabetes mellitus
  • Combination of Linagliptin, a DPP-4 inhibitor, and Metformin Hydrochloride, a biguanide
  • Immediate release and extended release dosage forms available
  • Dosage individualized based on effectiveness and tolerability
  • Cautions for renal impairment, metabolic acidosis, and hypersensitivity
  • Potential interactions with cationic drugs, carbonic anhydrase inhibitors, and inducers of P-glycoprotein and CYP3A4 enzymes
  • Common side effects include nasopharyngitis, diarrhea, and hypoglycemia
  • Use during pregnancy and lactation only if clearly needed
  • Precautions for lactic acidosis, acute pancreatitis, iodinated contrast materials, and Vitamin B12 levels
  • Hypoglycemia management, alcohol consumption, other medicines, counseling, travel, emergency preparedness, and medical identification
  • Overdose effects and supportive measures
  • Therapeutic class of oral hypoglycemic preparations
  • Storage in a cool, dry place below 30°C, protected from light and moisture

Dimensions

  • Various tablet sizes available

Color Options

  • Not applicable

Functions

  • Improves glycemic control
  • Stimulates insulin release
  • Decreases glucagon secretion
  • Lowers plasma glucose levels
  • Increases insulin sensitivity
  • Decreases hepatic glucose production
  • Improves peripheral glucose uptake and utilization

Materials

  • Active ingredients: Linagliptin, Metformin Hydrochloride

Technical Specifications

  • Maximum recommended doses: 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily for immediate release tablets
  • Maximum recommended doses: 5 mg Linagliptin and 2000 mg Metformin Hydrochloride once daily for extended release tablets
  • Hemodialysis or peritoneal dialysis unlikely to remove Linagliptin but dialyzable for Metformin Hydrochloride

Design Elements

  • Dosage individualization
  • Immediate release and extended release formats
  • Tablet formulation

Usability Features

  • Cautions for renal impairment
  • Recommendations for gradual dose escalation
  • Individualized starting doses based on patient's current treatment
  • Cautions for drug interactions and contraindications
  • Management of common side effects and overdose effects
  • Storage instructions

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