Ligazid M 2.5 mg+1000 mg (Tablet)

Unit Price: ৳ 16.00 (3 x 6: ৳ 288.00)

Strip Price: ৳ 96.00

Medicine Details

Category	Details
Generic	Linagliptin metformin hydrochloride
Company	Eskayef pharmaceuticals ltd
Also available as	Ligazid m 25 mg tablet Ligazid m 25 mg tablet Ligazid mx 5 mg tablet

Indications

Adjunct to diet and exercise
Improves glycemic control
Adults with type 2 diabetes mellitus

Pharmacology

Inhibitor of DPP-4 enzyme
Increases active incretin hormones
Stimulates insulin release
Decreases glucagon secretion
Oral antihyperglycemic drug
Lowers plasma glucose
Improves insulin sensitivity

Dosage & Administration

Individualized dosage
Maximum recommended dose
Dose escalation
Immediate release tablet
Extended release tablet
Starting dose recommendations
Tablet intake instructions

Interaction

Cationic Drugs interaction
Carbonic Anhydrase Inhibitors interaction
P-glycoprotein and CYP3A4 Enzymes interaction
Drugs Affecting Glycemic Control interaction

Contraindications

Renal impairment
Metabolic acidosis
Hypersensitivity

Side Effects

Nasopharyngitis
Diarrhea
Hypoglycemia

Pregnancy & Lactation

Use during pregnancy if clearly needed
Caution in lactating mothers

Precautions & Warnings

Discontinue in lactic acidosis
Discontinue in pancreatitis suspected
Temporary discontinuation for radiologic studies
Monitoring of Vitamin B12 levels
Symptoms of lactic acidosis
Impact of alcohol and other medicines
Counseling recommendations
Travel precautions
Emergency preparedness
Potential for hypoglycemia

Overdose Effects

Supportive measures for overdose
Hemodialysis or peritoneal dialysis for Metformin Hydrochloride
No dose-related clinical adverse drug reactions for Linagliptin
Hypoglycemia and lactic acidosis in Metformin Hydrochloride overdose

Therapeutic Class

Combination Oral hypoglycemic preparations

Storage Conditions

Cool and dry storage
Protection from light and moisture
Keep out of the reach of children

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