Nitrogina SR 2.6 mg (Tablet (Sustained Release))
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Nitroglycerin tablet |
Company | Nipro jmi pharma ltd |
Indications
- Prophylaxis of angina pectoris
Pharmacology
- Causes relaxation of vascular smooth muscle
- Produces a vasodilator effect on peripheral arteries and veins
- Reduces left ventricular end-diastolic pressure (preload)
- Reduces systemic vascular resistance and arterial pressure (afterload)
Dosage & Administration
- Dosage should be adjusted according to individual patient's requirement
- For adults, one Nitroglycerin 2.6 mg sustained released tablet in morning and evening
- Should be taken empty stomach
Interaction
- May increase the antihypertensive properties of vasodilators, calcium antagonists, beta-adrenergic blockers
- Concomitant use with tricyclic antidepressants and alcohol may cause high blood pressure
- Concomitant use with phosphodiesterase type 5 (PDE5) inhibitors may cause fall in blood pressure
Contraindications
- Known hypersensitivity to nitroglycerin or other organic nitrates
- Acute myocardial infarction
- Marked anaemia
- Head trauma
- Cerebral haemorrhage
- Closed angle glaucoma
Side Effects
- Headache
- Tachycardia
- Postural hypotension
- Syncope
- Cyanosis
- Methaemoglobinaemia
Pregnancy & Lactation
- No evidence of safety in pregnancy and lactation
- Should be administered to pregnant women and nursing mothers only if considered essential by the physician
Precautions & Warnings
- Use with caution in patients predisposed to closed-angle glaucoma
- Abrupt discontinuation may lead to exacerbation of symptoms
- Dosage reduction over several days upon discontinuation of long term treatment
Overdose Effects
- Peripheral vasodilation with a fall in blood pressure
- Reflex tachycardia
Therapeutic Class
- Nitrates: Coronary vasodilators
Storage Conditions
- Cool and dry place away from light and heat
- Keep out of the reach of children
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