Nitrogina SR 2.6 mg (Tablet (Sustained Release))

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Nitroglycerin tablet
Company Nipro jmi pharma ltd

Indications

  • Prophylaxis of angina pectoris

Pharmacology

  • Causes relaxation of vascular smooth muscle
  • Produces a vasodilator effect on peripheral arteries and veins
  • Reduces left ventricular end-diastolic pressure (preload)
  • Reduces systemic vascular resistance and arterial pressure (afterload)

Dosage & Administration

  • Dosage should be adjusted according to individual patient's requirement
  • For adults, one Nitroglycerin 2.6 mg sustained released tablet in morning and evening
  • Should be taken empty stomach

Interaction

  • May increase the antihypertensive properties of vasodilators, calcium antagonists, beta-adrenergic blockers
  • Concomitant use with tricyclic antidepressants and alcohol may cause high blood pressure
  • Concomitant use with phosphodiesterase type 5 (PDE5) inhibitors may cause fall in blood pressure

Contraindications

  • Known hypersensitivity to nitroglycerin or other organic nitrates
  • Acute myocardial infarction
  • Marked anaemia
  • Head trauma
  • Cerebral haemorrhage
  • Closed angle glaucoma

Side Effects

  • Headache
  • Tachycardia
  • Postural hypotension
  • Syncope
  • Cyanosis
  • Methaemoglobinaemia

Pregnancy & Lactation

  • No evidence of safety in pregnancy and lactation
  • Should be administered to pregnant women and nursing mothers only if considered essential by the physician

Precautions & Warnings

  • Use with caution in patients predisposed to closed-angle glaucoma
  • Abrupt discontinuation may lead to exacerbation of symptoms
  • Dosage reduction over several days upon discontinuation of long term treatment

Overdose Effects

  • Peripheral vasodilation with a fall in blood pressure
  • Reflex tachycardia

Therapeutic Class

  • Nitrates: Coronary vasodilators

Storage Conditions

  • Cool and dry place away from light and heat
  • Keep out of the reach of children

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