Lovapres 5 mg (Tablet)
Unit Price: ৳ 5.50 (5 x 10: ৳ 275.00)
Strip Price: ৳ 55.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Nipro jmi pharma ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
Dosage & Administration
- Usual dose is 5 mg once daily for hypertension
- Maximum dose is 10 mg once daily
- Usual dose for angina is 5-10 mg
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- Absence of interactions with Digoxin
- No interaction with Cimetidine
- No significant alteration of Warfarin effect
- Food does not alter the absorption rate
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy if benefits justify risks
- Recommendation to discontinue nursing while administered
Precautions & Warnings
- Precaution in patients with hepatic impairment
- Precaution during pregnancy and breastfeeding
Use in Special Populations
- Starting dose for children with hypertension 2.5 mg once daily
- No known effect on blood pressure in children under 6 years old
- Normal dosage regimens recommended in elderly
- Normal dosage recommended in renal impairment
- Caution in dose selection for hepatic impairment
- Initiation at lowest dose for severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Systemic hypotension up to shock with fatal outcome
- Active cardiovascular support for clinically significant hypotension
- Gastric lavage may be worthwhile in some cases
- Dialysis not likely to be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in cool & dry place
- Protected from light