Meroxin 500 mg/vial (IV Injection or Infusion)
Medicine Details
Category | Details |
---|---|
Generic | Meropenem trihydrate |
Company | Nipro jmi pharma ltd |
Also available as |
Indications
- Pneumonia and Nosocomial Pneumonia
- Urinary Tract Infections
- Intra-abdominal Infections
- Gynaecological Infections
- Skin and Skin Structure Infections
- Meningitis
- Septicaemia
- Pulmonary infections in cystic fibrosis
- Empiric treatment for presumed infections in patients with febrile neutropenia
Pharmacology
Bactericidal action by interfering with bacterial cell wall synthesis, penetrates bacterial cell walls, stable to all serine beta-lactamases, affinity for Penicillin Binding Proteins, activity against a broad spectrum of Gram-positive and Gram-negative bacteria
Dosage
- Recommended daily dosage for adults
- Recommended daily dosage for children
- Dosage for different types of infections including pneumonia, urinary tract infections, gynaecological infections, nosocomial pneumonias, peritonitis, intra-abdominal infections, cystic fibrosis, and meningitis
Administration
Administered by intravenous Infusion over approximately 15-30 minutes or as intravenous bolus over approximately 3-5 minutes
Interaction
Competes with Meroxin for active tubular secretion, inhibits renal excretion, may reduce serum valproic acid levels
Contraindications
Hypersensitivity to Meroxin
Side Effects
- Inflammation at injection site
- Thrombophlebitis
- Skin reactions like rash, pruritus, urticaria
- Abdominal pain
- Nausea
- Vomiting
- Diarrhea
- Headache
Pregnancy & Lactation
Pregnancy Category B, caution during breastfeeding
Precautions & Warnings
Discontinue if allergic reaction occurs, monitor liver function in hepatic disease
Use in Special Populations
- Renal impairment
- Hepatic impairment
- Elderly population
- Use in Children
Overdose Effects
Accidental overdose could occur, treatment should be symptomatic
Therapeutic Class
Other beta-lactam antibiotics
Reconstitution
- Preparation of solution for intravenous bolus administration
- Preparation of solution for intravenous infusion administration
- Compatibility with various infusion fluids
Storage Conditions
Store below 30°C, away from light & moisture, keep out of the reach of children
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