Neotack 75 mg/5 ml (Syrup)

100 ml bottle: ৳ 50.00

Medicine Details

Indications

  • Treatment of active duodenal ulcer
  • Benign gastric ulcer
  • Prevention of ulcer associated with non-steroidal anti-inflammatory agent
  • Post-operative stress ulcer
  • Zollinger-Ellison Syndrome
  • Gastroesophageal reflux disease (GERD)
  • Gastrointestinal hemorrhage from stress ulcer in seriously ill patients
  • Recurrent hemorrhage in patients with bleeding peptic ulcer
  • Prevention of acid aspiration before general anesthesia in at-risk patients

Pharmacology

  • Competitive blocking of histamine at H2-receptors
  • Inhibition of gastric acid secretion
  • No effect on pepsin secretion, intrinsic factor secretion, or serum gastrin

Dosage & Administration

  • Usual dosage of 150 mg twice daily for 4 to 8 weeks for duodenal and gastric ulcer
  • Dosage of 150 mg twice daily for up to 8 weeks for reflux esophagitis
  • Dosage of 150 mg 3 times daily for Zollinger-Ellison syndrome
  • Dosage of 150 mg twice daily for episodic dyspepsia
  • Maintenance dosage of 150 mg at night for preventing recurrences
  • Child dosage of 2-4 mg/kg twice daily, maximum 300 mg daily for peptic ulcer

Interaction

  • Delayed absorption and increased peak serum concentration with propantheline bromide
  • Minimal inhibition of hepatic metabolism of certain drugs

Contraindications

  • Hypersensitivity to Ranitidine

Side Effects

  • Altered bowel habit
  • Dizziness
  • Rash
  • Tiredness
  • Reversible confusional states
  • Headache
  • Decreased blood counts
  • Muscle or joint pain

Pregnancy & Lactation

  • Crosses the placenta
  • Excreted in human breast milk
  • Caution advised during lactation

Precautions & Warnings

  • Reduced dosage for impaired renal and hepatic function

Use in Special Populations

  • Ulcer healing rates similar in elderly patients
  • No difference in adverse effects in elderly patients

Overdose Effects

  • Specific in action, no particular problems expected

Therapeutic Class

  • H2 receptor antagonist

Reconstitution

  • Slow IV and intermittent slow IV infusion instructions

Storage Conditions

  • Store in a cool and dry place
  • Protect from light

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