Gitabin 200 mg/vial (IV Infusion)

200 mg vial: ৳ 1,950.00

Medicine Details

Category Details
Generic Gemcitabine
Company Bots pvt limited
Also available as
Gitabin 1 gm injection

Title and Categories

  • Gitabin (Gemcitabine) Injection
  • Cytotoxic Chemotherapy

Indications

  • First-line treatment for locally advanced or metastatic non-small cell lung cancer
  • Treatment of locally advanced or metastatic adenocarcinoma of the pancreas
  • Treatment of advanced bladder cancer in combination with Cisplatin
  • Treatment of metastatic breast cancer in combination with Paclitaxel
  • Treatment of recurrent epithelial ovarian carcinoma in combination with Carboplatin

Pharmacology

  • Metabolized intracellularly by nucleoside kinases
  • Cytotoxic action due to inhibition of DNA synthesis
  • Action of dFdCDP and dFdCTP on DNA synthesis
  • Induction of apoptosis

Dosage & Administration

  • Recommended dosage for non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer, and ovarian cancer
  • Dosing regimens for single-agent use and combination use

Interaction

  • No confirmed drug interactions reported

Contraindications

  • Contraindicated in patients with known hypersensitivity to Gemcitabine or any other components

Side Effects

  • Haematological Toxicity
  • Hepatic Toxicity
  • Gastrointestinal effects
  • Genito-Urinary Toxicity
  • Pulmonary Toxicity
  • Allergic Toxicity
  • Neurotoxicity
  • Alopecia

Pregnancy & Lactation

  • Pregnancy Category D
  • Use during pregnancy and lactation

Precautions & Warnings

  • Caution in patients with Schedule-dependent Toxicity, Myelosuppression, Pulmonary Toxicity, Respiratory Failure, Hemolytic Uremic Syndrome, Hepatic Toxicity, Embryofetal Toxicity, Radiation Therapy Toxicity, and Impairment of Fertility

Use in Special Populations

  • Elderly Patients
  • Renal and Hepatic Impairment
  • Children

Overdose Effects

  • No known antidote for overdoses
  • Monitoring and supportive therapy in suspected overdose

Therapeutic Class

  • Cytotoxic Chemotherapy

Storage Conditions

  • Store at 20°C to 25°C
  • Keep away from light
  • Do not refrigerate

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