Carboplatin Sindan 10 mg/ml (IV Infusion)
450 mg vial: ৳ 4,140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Carboplatin |
| Company | Bots pvt limited |
Indications
- Initial treatment of advanced ovarian carcinoma
- Palliative treatment of recurrent ovarian carcinoma
Pharmacology
- Alkylating agent
- Binds covalently to DNA
- Modifies cell cycle
Dosage & Administration
- Intravenous route only
- Recommended dosage of 400 mg/m2
- Dosage adjustment based on hematologic nadir
- Proper handling and disposal procedures for anti-cancer drugs
Interaction
- Not to be mixed with other drugs
- Potentiation of renal effects of neurotoxic compounds
Contraindications
- Severe renal impairment
- Severe myelosuppression
- History of severe allergic reactions to Carboplatin
- Patients with bleeding tumors
Side Effects
- Haematologic toxicity
- Nephrotoxicity
- Gastrointestinal toxicity
- Allergic reactions
- Hepatic toxicity
- Neurotoxicity
Pregnancy & Lactation
- Pregnancy Category D
- Presence in human milk
- Excretion in human
Precautions & Warnings
- Administered under supervision of qualified physician
- Close monitoring of peripheral blood counts, renal and hepatic function
- Cautious combination therapy with myelosuppressive compounds
- Frequent monitoring of peripheral blood counts
- Supportive transfusional therapy might be required
- Potential for nausea, vomiting, and renal function impairment
- Allergic reactions may occur within five minutes of administration
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Store below 25°C in a dry place
- Do not refrigerate
- Keep out of reach of children
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