Normacid 150 mg (Tablet)
Unit Price: ৳ 2.51 (100's pack: ৳ 251.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Kemiko pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastrointestinal hemorrhage from stress ulcer in seriously ill patient
- Recurrent hemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patient considered to be at risk of acid aspiration particularly obstetric patients
Pharmacology
- Competitively blocks histamine at H2-receptors
- Inhibits gastric acid secretion
- Does not affect pepsin secretion
- Does not affect pentagastrin-stimulated intrinsic factor secretion
- Does not affect serum gastrin
Dosage & Administration
- Usual dosage of 150 mg twice daily for active duodenal and benign gastric ulcer
- Usual dosage of 300 mg as a single daily dose at night for 4 to 8 weeks for duodenal and gastric ulcer
- Dosage of 150 mg twice daily for reflux esophagitis
- Dosage of 150 mg 3 times daily for Zollinger Ellison syndrome
- Dosage of 150 mg twice daily for episodic dyspepsia
- Maintenance dosage of 150 mg at night for preventing recurrences
- Dosage of 2-4 mg/kg twice daily for children with peptic ulcer
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Caution should be exercised when administered to a nursing mother
Precautions & Warnings
- Reduced dosage for patients with impaired renal and hepatic function
Use in Special Populations
- Similar ulcer healing rates in elderly patients
- No difference in incidence of adverse effects in elderly patients
Overdose Effects
- No particular problems expected following overdosage
- Symptomatic and supportive therapy should be given as appropriate
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Different dilution concentrations for slow IV injection, intermittent slow IV infusion, and continuous IV infusion
- Specific dilution recommendations for patients with hypersecretory conditions
Storage Conditions
- Store in a cool and dry place
- Protect from light