Erlotin 150 mg (Tablet)
Unit Price: ৳ 1,000.00 (3 x 10: ৳ 30,000.00)
Strip Price: ৳ 10,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erlotinib |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Title and Category
- Erlotin - Kinase Inhibitor
- Therapeutic Class: Targeted Cancer Therapy
Description
- N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)4-quinazolinamine
- Reversibly inhibits EGFR kinase activity
- Prevents autophosphorylation of tyrosine residues
- Higher binding affinity for certain EGFR mutations
Dosage and Administration
- Recommended daily doses for NSCLC and Pancreatic Cancer
- Specific instructions for taking Erlotinib on an empty stomach
- Guidelines for dose reductions and increments based on concomitant medication or smoking
Interaction
- Interactions with anticoagulants
- Metabolism by CYP3A4 enzyme
- Effects of CYP3A4 inhibitors and inducers
- Effect of drugs affecting gastric pH
Side Effects
- Common adverse reactions
- Serious adverse reactions and potential fatalities
Pregnancy and Lactation
- Pregnancy Category D
- Potential presence in human milk
- Consideration for nursing mothers
Precautions and Warnings
- Risk of Interstitial Lung Disease (ILD)
- Monitoring for renal failure and hepatotoxicity
- Adverse reactions related to specific organ systems
Use in Special Populations
- Pediatric use
- Geriatric use
Overdose Effects
- Tolerance levels observed in healthy subjects and cancer patients
- Potential severe adverse reactions
- Guidelines for suspected overdose
Storage Conditions
- Recommended temperature and storage instructions