Erlotin 100 mg (Tablet)
Unit Price: ৳ 750.00 (3 x 10: ৳ 22,500.00)
Strip Price: ৳ 7,500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erlotinib |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Title
- Erlotinib 150 mg Tablets
Categories
- Medicine
- Cancer Treatment
Description
- A kinase inhibitor used for the treatment of metastatic Non-Small Cell Lung Cancer (NSCLC) and pancreatic cancer
- Chemical name: N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)4-quinazolinamine
- Reversibly inhibits the kinase activity of EGFR
DosageInstructions
- Recommended daily dose for NSCLC: 150 mg on an empty stomach
- Recommended daily dose for pancreatic cancer: 100 mg in combination with gemcitabine
- Dosage adjustments with concomitant use of CYP3A4 inhibitors and inducers
Interaction
- Interacts with coumarin-derived anticoagulants, CYP3A4 inhibitors, CYP3A4 inducers, and drugs affecting gastric pH
SideEffects
- Common adverse reactions: rash, diarrhea, anorexia, fatigue, dyspnea, cough, nausea, vomiting
- Serious adverse reactions such as Interstitial Lung Disease (ILD), Renal Failure, Gastrointestinal Perforation, and others
PregnancyAndLactation
- Category D drug with potential to cause fetal harm when administered to a pregnant woman
- Not known if present in human milk. Decision should be made whether to discontinue nursing
PrecautionsAndWarnings
- Specific precautions including monitoring for Interstitial Lung Disease (ILD), Renal Failure, Hepatotoxicity, Gastrointestinal perforations, and others
SpecialPopulations
- Pediatric use: Safety and effectiveness not established
- Geriatric use: No overall differences in safety or efficacy observed in subjects 65 years and older
OverdoseEffects
- Single oral doses of up to 1,000 mg in healthy subjects have been tolerated
- Repeated doses above recommended levels may lead to severe adverse reactions such as diarrhea, rash, and liver transaminase elevation
TherapeuticClass
- Targeted Cancer Therapy
StorageConditions
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light and moisture