Initer 3000 IU (IV/SC Injection)
3000 IU pre-filled syringe: ৳ 1,477.78
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of anemia in Chronic Kidney Disease (CKD) patients
- Treatment of anemia in HIV-infected patients receiving Zidovudine
- Reduction of allogeneic RBC transfusions in noncardiac, nonvascular surgery patients
- Prevention of anemia of prematurity in infants with low birth weight
Description
- Recombinant human erythropoietin (EPO)
- Expressed in Chinese hamster ovary cells
- 165 amino acid sequence identical to human urinary EPO
- Apparent molecular weight of about 30,400 daltons
Dosage
- Evaluation of iron stores and nutritional factors before treatment
- Monitoring hemoglobin levels weekly during initiation or adjustment of therapy
- Dose adjustment based on hemoglobin response
- Specific dosing recommendations for CKD patients on dialysis and not on dialysis, Zidovudine-treated HIV-infected patients, and cancer chemotherapy patients
Administration
- Preparation and administration guidelines
- Caution against shaking or freezing the product
- Visual inspection for particulate matter and discoloration before administration
Interaction
- Potentiation with simultaneous administration of haematinic agents in deficiency states
Contraindications
- Uncontrolled hypertension
- Allergic reactions to Erythropoietin alfa
- Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
Side Effects
- List of adverse reactions in CKD patients, Zidovudine-treated HIV-infected Patients, cancer patients on chemotherapy, surgery patients, and premature infants
Pregnancy & Lactation
- Use in pregnancy only if potential benefit outweighs potential risk to the foetus
- Caution in nursing women
Overdose Effects
- Potential effects of Initer overdosage
- Recommendations for managing elevated hemoglobin levels
Therapeutic Class
- Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
- Store at 2°C to 8°C
- Avoid freezing or shaking
- Protection from light