Initer 10000 IU (IV/SC Injection)

10000 IU pre-filled syringe: ৳ 5,001.73

Medicine Details

Category Details
Generic Erythropoietin alfa
Company Healthcare pharmaceuticals ltd
Also available as
Initer 2000 iu injection Initer 3000 iu injection Initer 5000 iu injection

Title

  • Initer - Recombinant Human Erythropoietin (EPO)
  • Initer

Category

  • Medicine
  • Pharmaceuticals
  • Healthcare

Description

Initer is a recombinant human erythropoietin (EPO) expressed in Chinese hamster ovary cells. It has a 165 amino acid sequence identical to that of human urinary EPO.

Indications

  • Treatment of anemia in Chronic Kidney Disease (CKD) patients on and not on dialysis
  • Treatment of anemia in Zidovudine-treated HIV-infected patients
  • Reduction of allogeneic RBC transfusions in noncardiac, nonvascular surgery patients
  • Prevention of anemia of prematurity in infants with low birth weight and gestational age

Dosage

  • Evaluation of iron stores and nutritional factors before and during treatment
  • Monitoring hemoglobin levels regularly for CKD patients
  • Initiating treatment based on hemoglobin levels for CKD patients on dialysis and not on dialysis, and Zidovudine-treated HIV-infected patients
  • Dose adjustments based on hemoglobin response, with specific guidelines for CKD patients and cancer patients on chemotherapy

Administration

  • Preparation and administration guidelines to ensure product integrity and patient safety

Interaction

  • Potential potentiation by concomitant administration of haematinic agents like ferrous sulphate in case of deficiency state

Contraindications

  • Uncontrolled hypertension
  • Serious allergic reactions to Erythropoietin alfa
  • Patients who develop Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin

Side Effects

  • Adverse reactions in treated patients in clinical studies
  • Specific side effects observed in CKD patients, Zidovudine-treated HIV-infected Patients, Cancer Patients on Chemotherapy, Surgery Patients, and Premature infants

Pregnancy & Lactation

  • Cautionary use during pregnancy and lactation due to limited studies in pregnant women and potential risk to the foetus

Overdose Effects

  • Clinical implications of Initer overdosage and management of hemoglobin levels

Therapeutic Class

  • Drugs for Haemolytic Hypoplastic & Renal Anemia

Storage Conditions

  • Recommended storage temperature and protection guidelines

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