Relyto 10 mg/ml (IV Infusion)

100 mg vial: ৳ 13,000.00

Medicine Details

Category Details
Generic Rituximab
Company Incepta pharmaceuticals ltd

Indications

  • Non-Hodgkin's Lymphoma treatment
  • Chronic Lymphocytic Leukemia treatment
  • Rheumatoid Arthritis treatment
  • Granulomatosis with Polyangiitis treatment
  • Pemphigus Vulgaris treatment
  • Treatment for different types of Non-Hodgkin's Lymphoma
  • Maintenance therapy for certain lymphomas

Pharmacology

  • Genetically engineered chimeric murine/human monoclonal IgG1 kappa antibody
  • Targeted against the CD20 antigen
  • Approximate molecular weight of 145 kD

Dosage & Administration

  • Intravenous administration only
  • Specific infusion rates for different conditions
  • Use in pediatric patients with mature B-cell NHL/B-AL

Interaction

  • No formal drug interaction studies performed
  • No alteration of systemic exposure to specific drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to Rituximab

Side Effects

  • Reactivation of hepatitis B virus
  • Various infusion-related reactions
  • Fever, rigors, pruritus, skin rashes
  • Hypotension, flushing, asthenia, headache
  • Hematological complications

Pregnancy & Lactation

  • Potential fetal harm
  • Adverse developmental outcomes
  • Advice against breastfeeding during treatment and 6 months after last dose

Precautions & Warnings

  • Severe, potentially fatal infusion-related reactions
  • Severe mucocutaneous reactions
  • Risk of Progressive Multifocal Leukoencephalopathy (PML)
  • Tumor Lysis Syndrome (TLS) risk
  • Risk of serious infections

Therapeutic Class

  • Cytotoxic immunosuppressants

Storage Conditions

  • Refrigeration at 2°C-8°C
  • Protection from light
  • Keep out of reach of children

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