Gemcetin 200 mg/vial (IV Infusion)
200 mg vial: ৳ 1,400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Gemcitabine |
| Company | Techno drugs ltd |
| Also available as |
Indications
- Non-Small Cell Lung Cancer
- Pancreatic Cancer
- Bladder Cancer
- Breast Cancer
- Ovarian Cancer
Pharmacology
- Metabolized intracellularly by nucleoside kinases
- Active diphosphate (dFdCDP) and triphosphate (dFdCTP) nucleosides
- Cytotoxic action due to inhibition of DNA synthesis
- Inhibition of ribonucleotide reductase
- Competes with dCTP for incorporation into DNA
- Induces programmed cellular death process
Dosage & Administration
- Recommended dose for Non-Small Cell Lung Cancer
- Recommended dose for Pancreatic Cancer
- Recommended dose for Bladder Cancer
- Recommended dose for Breast Cancer
- Recommended dose for Ovarian Cancer
- Dosage reduction based on toxicity experienced
Interaction
- No confirmed interactions reported
- No specific drug interaction studies conducted
Contraindications
- Contraindicated in patients with known hypersensitivity to Gemcitabine
Side Effects
- Haematological Toxicity
- Hepatic Toxicity
- Gastrointestinal
- Genito-Urinary Toxicity
- Pulmonary Toxicity
- Allergic Toxicity
- Neurotoxicity
- Alopecia
Pregnancy & Lactation
- Pregnancy Category D
- Use during pregnancy
- Unknown excretion in human breast milk
Precautions & Warnings
- Caution in patients with risk of Schedule-dependent Toxicity
- Myelosuppression
- Pulmonary Toxicity and Respiratory Failure
- Hemolytic Uremic Syndrome
- Impairment of Fertility
Use in Special Populations
- Elderly Patients
- Renal and Hepatic Impairment
- Children
Overdose Effects
- No known antidote
- Myelosuppression
- Paresthesias
- Severe rash
- Patient monitoring with appropriate blood counts
- Supportive therapy
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Store the vial in original carton at 20°C to 25°C
- Away from light
- Do not refrigerate
- Keep out of the reach of children