Apetiz 160 mg (Tablet)
Unit Price: ৳ 90.00 (3 x 10: ৳ 2,700.00)
Strip Price: ৳ 900.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Megestrol acetate |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Palliative treatment of advanced carcinoma of the breast
- Palliative treatment of endometrium carcinoma
- Treatment of anorexia in patients with Acquired Immunodeficiency Syndrome (AIDS)
- Treatment of cachexia in patients with Acquired Immunodeficiency Syndrome (AIDS)
- Treatment of significant weight loss in patients with a diagnosis of cancer
Pharmacology
- Synthetic, antineoplastic and progestational drug
- Mechanism of action against endometrial carcinoma
- Mechanism of action against breast carcinoma
- Plasma levels and peak concentration
- Plasma half-life
- Excretion percentage in urine and faeces
Dosage & Administration
- Dosage for breast cancer
- Dosage for endometrial carcinoma
- Duration of continuous treatment for efficacy determination
- Recommended adult initial dosage for oral suspension
Interaction
- Possible interactions with concomitant medications
- Potential fluid retention with estrogens and progestogens therapy
Contraindications
- Hypersensitivity to Megestrol Acetate
- Hypersensitivity to any component of the formulation
- Known or suspected pregnancy
Side Effects
- Weight gain
- Thromboembolic phenomena
- Glucocorticoid effects
- Nausea
- Dyspnea
- Tumor flare
- Hyperglycemia
- Glucose intolerance
- Alopecia
- Hypertension
- Carpal tunnel syndrome
- Mood changes
- Hot flashes
- Malaise
- Asthenia
- Lethargy
- Sweating
- Rash
Pregnancy & Lactation
- Pregnancy Category D
- Excretion in mother's milk
- Harmful effect on the newborn
- Discontinuation of nursing during treatment
Precautions & Warnings
- Close surveillance for patient with recurrent or metastatic cancer
- Use with caution in patients with a history of thromboembolic disease
- Exacerbation of preexisting diabetes
Use in Special Populations
- No established safety and effectiveness in pediatric patients
- Insufficient data availability for patients 65 years of age and older
Overdose Effects
- Lack of serious unexpected side effects from studies involving high dosages
Storage Conditions
- Temperature and moisture conditions for storage
- Keep out of reach of children