Sonexa 4 mg (Tablet)

Unit Price: ৳ 11.00 (2 x 10: ৳ 220.00)
Strip Price: ৳ 110.00

Medicine Details

Indications

  • Control of severe or incapacitating allergic conditions
  • Treatment of asthma, atopic dermatitis, contact dermatitis, allergic rhinitis
  • Treatment of collagen diseases like lupus erythematosus, rheumatoid arthritis
  • Management of dermatologic diseases like pemphigus, erythema multiforme
  • Treatment of endocrine disorders such as adrenocortical insufficiency, hypercalcemia
  • Management of gastrointestinal diseases like enteritis, ulcerative colitis
  • Control of neoplastic diseases like leukemias and lymphomas
  • Treatment of nervous system conditions like multiple sclerosis, cerebral edema
  • Management of ophthalmic diseases like temporal arteritis, uveitis
  • Induction of diuresis or remission of proteinuria in renal diseases
  • Treatment of respiratory diseases like pulmonary tuberculosis, sarcoidosis
  • Adjunctive therapy for rheumatic disorders like rheumatoid arthritis, gouty arthritis
  • Diagnostic testing of adrenocortical hyperfunction

Pharmacology

  • Synthetic glucocorticoid
  • Decreases inflammation
  • Inhibits migration of leukocytes
  • Reverses increased capillary permeability
  • Suppresses normal immune response

Dosage & Administration

  • Oral dosages vary from 1 mg to 10 mg for adults
  • Oral dosages vary from 0.03-0.20 mg/kg body weight for children
  • Higher dosages may be temporarily required in some patients
  • Intravenous, intramuscular, or local injection administration
  • Dosage depends on the severity of the condition and patient response

Interaction

  • Potassium loss enhancement with diuretics and cardiac glycosides
  • Impaired glucose tolerance with antidiabetics
  • Increased incidence of gastrointestinal ulceration with non-steroidal anti-inflammatory drugs

Contraindications

  • Gastric and duodenal ulcers
  • Systemic and ophthalmic fungal infections
  • Viral infections like varicella and herpes genitalis
  • Glaucoma
  • Hypersensitivity to corticosteroids

Side Effects

  • Cushing-like syndrome
  • Hirsutism
  • Osteoporosis
  • Gastric and duodenal ulceration
  • Impaired wound healing
  • Increased susceptibility to infections

Pregnancy & Lactation

  • Pregnancy Category C
  • Use only if potential benefit justifies potential risk to fetus
  • Appear in breast milk

Precautions & Warnings

  • Use lowest possible dose to control the condition
  • Caution in patients with congestive heart failure, hypertension, renal insufficiency
  • Minimize drug-induced secondary adrenocortical insufficiency by gradual reduction of dosage

Use in Special Populations

  • Pediatric patients should be titrated to the lowest effective dose to minimize potential growth effects

Overdose Effects

  • Unlikely
  • Treatment by supportive and symptomatic therapy

Storage Conditions

  • Tablet: Store in cool & dry place, protected from light & moisture
  • Injection: Store below 30°C, protected from light, do not freeze

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