Docetaxel HEXAL 20 mg/vial (IV Infusion)
20 mg vial: ৳ 3,540.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Docetaxel trihydrate |
| Company | Sandoz a novartis division |
| Also available as |
Indications
- Breast Cancer treatment
- Non-small Cell Lung Cancer treatment
- Castration-Resistant Prostate Cancer treatment
- Gastric Adenocarcinoma treatment
- Squamous Cell Carcinoma of the Head and Neck treatment
Pharmacology
- Microtubule inhibitor
- Disrupts microtubular network
- Inhibits mitosis in cells
- Cytotoxic to tumor cell lines
Dosage & Administration
- Intravenous administration
- Dosage based on cancer type and treatment status
- Premedication with oral corticosteroids
Interaction
- CYP3A4 substrate
- Metabolism modified by concomitant administration of certain compounds
Contraindications
- Neutrophil counts < 1500 cells/mm^3
- Severe hypersensitivity reactions to docetaxel or polysorbate 80
Side Effects
- Infections
- Neutropenia
- Anemia
- Hypersensitivity
- Thrombocytopenia
- Neuropathy
- Dysgeusia
- Constipation
- Anorexia
- Nail disorders
- Fluid retention
- Asthenia
- Nausea
- Diarrhea
- Vomiting
- Mucositis
- Alopecia
- Skin reactions
- Myalgia
Pregnancy & Lactation
- Potential fetal harm
- No information on presence in human milk or effects on breastfed child
Precautions & Warnings
- Higher risk in patients with hepatic impairment
- Neutrophil count monitoring
- Severe hypersensitivity reaction monitoring
- Risk of treatment-related acute myeloid leukemia
Overdose Effects
- No known antidote
- Close monitoring of vital functions
- Expected exacerbation of adverse events
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Store between 2°C and 25°C
- Protected from light
- Freezing does not adversely affect the product