Oxaliplatin AqVida 5 mg/ml (IV Infusion)

50 mg vial: ৳ 3,693.00

Medicine Details

Category Details
Generic Oxaliplatin
Company Aqvida gmbh

Indications

  • Adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor
  • Treatment of advanced colorectal cancer

Pharmacology

  • Formation of reactive species
  • Crosslinks inhibition of DNA replication and transcription
  • Antitumor activity against colon carcinoma
  • In vitro and in vivo antiproliferative activity

Dosage & Administration

  • Recommended dosage for advanced disease
  • Treatment duration for adjuvant use
  • Specific administration instructions for Day 1 and Day 2

Interaction

  • No specific cytochrome P-450-based drug interaction studies conducted
  • Increase of 5-fluorouracil plasma concentrations observed with certain Oxaliplatin doses
  • Potential interaction with nephrotoxic compounds

Contraindications

  • Known allergy to oxaliplatin or other platinum compounds

Side Effects

  • Common adverse reactions such as peripheral sensory neuropathy, neutropenia, thrombocytopenia, nausea, and more
  • Reported serious adverse reactions

Pregnancy & Lactation

  • Pregnancy Category D
  • Advice for women of childbearing potential
  • Excretion in human milk and potential adverse reactions in nursing infants

Precautions & Warnings

  • Grade 3/4 hypersensitivity and management
  • Neurological toxicity monitoring and precautions
  • Pulmonary, hepatotoxicity, and cardiovascular precautions
  • ECG monitoring and avoidance in patients with congenital long QT syndrome

Overdose Effects

  • No known antidote
  • Anticipated complications of overdose
  • Reported adverse reactions in cases of overdose
  • Supportive treatment and maximum administered dose

Therapeutic Class

  • Cytotoxic Chemotherapy

Storage Conditions

  • Cool & dry storage
  • Protection from light and moisture
  • Keep out of reach of children

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