Docetaxel AqVida 20 mg/vial (IV Infusion)
20 mg vial: ৳ 3,700.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Docetaxel trihydrate |
| Company | Aqvida gmbh |
| Also available as |
Indications
- Breast Cancer treatment
- Non-small Cell Lung Cancer treatment
- Castration-Resistant Prostate Cancer treatment
- Gastric Adenocarcinoma treatment
- Squamous Cell Carcinoma of the Head and Neck treatment
Pharmacology
- Antineoplastic agent
- Disrupts microtubular network
- Promotes assembly of tubulin
- Inhibits microtubule disassembly
- Cytotoxic to tumor cell lines
Dosage & Administration
- Administered intravenously
- Administered every 3 weeks
- Different dosage for different indications
- Premedication with oral corticosteroids
- Adjustable dosage
Interaction
- CYP3A4 substrate
- Metabolism modification by concomitant administration of certain compounds
Contraindications
- Neutrophil counts below 1500 cells/mm3
- History of severe hypersensitivity to docetaxel or polysorbate 80
Side Effects
- Infections
- Neutropenia
- Anemia
- Hypersensitivity
- Neuropathy
- Constipation
- Alopecia
- Nail disorders
- Fluid retention
- Nausea
- Vomiting
- Mucositis
- Skin reactions
- Myalgia
Pregnancy & Lactation
- Can cause fetal harm
- No information on presence in human milk
- No lactation studies in animals
Precautions & Warnings
- Higher risk in patients with hepatic impairment
- Severe hypersensitivity reactions
- Treatment-related acute myeloid leukemia
Overdose Effects
- No known antidote
- Complications include bone marrow suppression
- Peripheral neurotoxicity
- Mucositis
Therapeutic Class
Cytotoxic Chemotherapy
Storage Conditions
Store between 2°C and 25°C, protected from light