Gluco-A 50 mg (Tablet)
Unit Price: ৳ 11.04 (2 x 10: ৳ 220.80)
Strip Price: ৳ 110.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Acarbose |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Improves glycemic control in adults with type 2 diabetes mellitus
Pharmacology
- Inhibition of pancreatic alpha-amylase and intestinal alpha-glucosidase enzymes
- Delayed glucose absorption
- Lowering of postprandial hyperglycemia
- Additive effect with sulfonylureas, insulin, or metformin
- Diminished insulinotropic and weight-increasing effects of sulfonylureas
- No inhibitory activity against lactase
Dosage & Administration
- Recommended starting dosage of 25 mg orally three times daily
- Gradual dose titration to minimize gastrointestinal side effects
- Dosage adjustment based on glucose levels and tolerance
- Maintenance dosage ranges from 50 mg t.i.d. to 100 mg t.i.d.
Interaction
- Certain drugs may produce hyperglycemia and lead to loss of blood glucose control
- Observation required when drugs are administered or withdrawn in combination with sulfonylureas or insulin
Contraindications
- Hypersensitivity to the drug
- Diabetic ketoacidosis or cirrhosis
- Inflammatory bowel disease, colonic ulceration, intestinal obstruction, or predisposition to intestinal obstruction
- Chronic intestinal diseases associated with digestion or absorption disorders
- Conditions deteriorating due to increased gas formation in the intestine
Side Effects
- Diarrhea
- Gas
- Upset stomach
- Constipation
- Stomach pain
- Adverse effects may improve with time and adherence to prescribed diet
Pregnancy & Lactation
- Pregnancy Category B
- Safety not established in pregnant women
- Unknown excretion in human milk
- Avoid administration to nursing women
Precautions & Warnings
- Unlikelihood of causing hypoglycemia when administered alone
- Increased potential for hypoglycemia when used in combination with sulfonylureas or insulin
- Use of oral glucose instead of sucrose for hypoglycemia treatment
- Severe hypoglycemia may require intravenous glucose infusion or glucagon injection
Use in Special Populations
- Pediatric use safety and effectiveness not established
- No overall differences in safety and effectiveness observed in geriatric use
Overdose Effects
- No hypoglycemia resulting from overdose
- Transient increases in flatulence, diarrhea, and abdominal discomfort
- Avoidance of carbohydrates for 4-6 hours in case of overdosage
Therapeutic Class
- Alpha-Glucosidase inhibitor
Storage Conditions
- Store below 25° C
- Protect from moisture