Peptil H 75 mg/5 ml (Syrup)

100 ml bottle: ৳ 45.00

Medicine Details

Title

  • Peptil H

Categories

  • Medicine
  • Gastrointestinal Health

Description

  • Peptil H is a H2 receptor antagonist indicated for the treatment of active duodenal ulcer, benign gastric ulcer, ulcer associated with non-steroidal anti-inflammatory agent, post-operative stress ulcer, Zollinger-Ellison Syndrome, and gastroesophageal reflux disease (GERD). It is available in tablet, syrup, and IV injection forms.

DosageRange

  • 150 mg to 300 mg per dose
  • 2-4 mg/kg for children
  • Oral and Intravenous administration

Pharmacology

  • Competitively blocks histamine at H2-receptors of the gastric parietal cells inhibiting gastric acid secretion

Interaction

  • Delayed absorption and increased peak serum concentration with propantheline bromide
  • Minimally inhibits hepatic metabolism of certain drugs
  • May alter absorption of pH-dependent drugs and reduce bioavailability with antacids

Contraindications

  • Hypersensitivity to ranitidine

SideEffects

  • Altered bowel habit
  • Dizziness
  • Rash
  • Tiredness
  • Reversible confusional states
  • Headache
  • Decreased blood counts
  • Muscle or joint pain

PregnancyAndLactation

  • Crosses the placenta
  • Excreted in human breast milk
  • Caution advised during pregnancy and lactation

PrecautionsAndWarnings

  • Reduced dosage in patients with impaired renal and hepatic function

UseInSpecialPopulations

  • Similar ulcer healing rates in elderly patients as in younger patients

OverdoseEffects

  • No particular problems expected
  • Symptomatic and supportive therapy recommended

TherapeuticClass

  • H2 receptor antagonist

Reconstitution

  • Slow IV injection
  • Intermittent slow IV infusion
  • Continuous IV infusion

StorageConditions

  • Store in a cool and dry place
  • Protect from light

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