Ranbex 150 mg (Tablet)
Unit Price: ৳ 1.25 (100's pack: ৳ 125.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Novo healthcare and pharma ltd |
Product Title
- Ranbex
Categories
- Medicine
- Pharmaceutical
Description
- Ranitidine competitively blocks histamine at H2-receptors of the gastric parietal cells which inhibits gastric acid secretion.
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
- Recurrent haemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patient considered to be at risk of acid aspiration particularly obstetric patients
Mode of Action
- Competitively blocks histamine at H2-receptors of the gastric parietal cells
Dosage & Administration
- Usual dosage is 150 mg twice daily taken in the morning and evening or 300 mg as a single daily dose at night for 4 to 8 weeks
- 150 mg twice daily or 300 mg at bedtime for up to 8 weeks for Reflux oesophagitis
- 150 mg 3 times daily for Zollinger Ellison syndrome
- 150 mg twice daily or 300 mg at bedtime for up to 6 weeks for Episodic dyspepsia
- 150 mg at night for preventing recurrences
- 2-4 mg/kg twice daily, maximum 300 mg daily for children (peptic ulcer)
- Various dosage for Ranitidine IV injection & IV Infusion.
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Excreted in human breast milk
Precautions & Warnings
- Should be given in reduced dosage to patients with impaired renal and hepatic function
Use in Special Populations
- Use in elderly patients
Overdose Effects
- No particular problems expected following overdosage
- Symptomatic and supportive therapy should be given as appropriate
- Drug may be removed from the plasma by haemodialysis
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Specific instructions for slow IV injection, intermittent slow IV infusion, continuous IV infusion
Storage Conditions
- Store in a cool and dry place, protect from light